GenomeNet

Database: UniProt
Entry: Q8QMY8_CWPXB
LinkDB: Q8QMY8_CWPXB
Original site: Q8QMY8_CWPXB 
ID   Q8QMY8_CWPXB            Unreviewed;        73 AA.
AC   Q8QMY8;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   12-AUG-2020, entry version 51.
DE   RecName: Full=Protein I2 {ECO:0000256|ARBA:ARBA00016360};
GN   Name=CPXV081 CDS {ECO:0000313|EMBL:AAM13526.1};
OS   Cowpox virus (strain Brighton Red) (CPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=265872 {ECO:0000313|EMBL:AAM13526.1, ECO:0000313|Proteomes:UP000152733};
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=9685; Felis catus (Cat) (Felis silvestris catus).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9785; Loxodonta africana (African elephant).
OH   NCBI_TaxID=29092; Microtus agrestis (Short-tailed field vole).
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
OH   NCBI_TaxID=447135; Myodes glareolus (Bank vole) (Clethrionomys glareolus).
RN   [1] {ECO:0000313|EMBL:AAM13526.1, ECO:0000313|Proteomes:UP000152733}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brighton Red {ECO:0000313|EMBL:AAM13526.1};
RX   PubMed=6961398; DOI=10.1073/pnas.79.23.7112;
RA   Pickup D.J., Bastia D., Stone H.O., Joklik W.K.;
RT   "Sequence of terminal regions of cowpox virus DNA: arrangement of repeated
RT   and unique sequence elements.";
RL   Proc. Natl. Acad. Sci. U.S.A. 79:7112-7116(1982).
RN   [2] {ECO:0000313|EMBL:AAM13526.1, ECO:0000313|Proteomes:UP000152733}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brighton Red {ECO:0000313|EMBL:AAM13526.1};
RX   PubMed=2309453; DOI=10.1016/0042-6822(90)90187-V;
RA   Parsons B.L., Pickup D.J.;
RT   "Transcription of orthopoxvirus telomeres at late times during infection.";
RL   Virology 175:69-80(1990).
RN   [3] {ECO:0000313|EMBL:AAM13526.1, ECO:0000313|Proteomes:UP000152733}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brighton Red {ECO:0000313|EMBL:AAM13526.1};
RX   PubMed=2014645; DOI=10.1016/0042-6822(91)90905-Q;
RA   Hu F.Q., Pickup D.J.;
RT   "Transcription of the terminal loop region of vaccinia virus DNA is
RT   initiated from the telomere sequences directing DNA resolution.";
RL   Virology 181:716-720(1991).
RN   [4] {ECO:0000313|EMBL:AAM13526.1, ECO:0000313|Proteomes:UP000152733}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brighton Red {ECO:0000313|EMBL:AAM13526.1};
RX   PubMed=8091665; DOI=10.1006/viro.1994.1539;
RA   Hu F.Q., Smith C.A., Pickup D.J.;
RT   "Cowpox virus contains two copies of an early gene encoding a soluble
RT   secreted form of the type II TNF receptor.";
RL   Virology 204:343-356(1994).
CC   -!- FUNCTION: Late protein which probably plays a role in virus entry into
CC       the host cell. {ECO:0000256|ARBA:ARBA00004101}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Virion membrane
CC       {ECO:0000256|ARBA:ARBA00004381}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004381}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I2 family.
CC       {ECO:0000256|ARBA:ARBA00007048}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF482758; AAM13526.1; -; Genomic_DNA.
DR   RefSeq; NP_619868.1; NC_003663.2.
DR   GeneID; 1485958; -.
DR   KEGG; vg:1485958; -.
DR   Proteomes; UP000152733; Genome.
DR   InterPro; IPR009175; Poxvirus_I2.
DR   Pfam; PF12575; Pox_EPC_I2-L1; 1.
DR   PIRSF; PIRSF003766; VAC_I2L; 1.
PE   3: Inferred from homology;
KW   Late protein {ECO:0000256|ARBA:ARBA00022921};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022595};
KW   Virion {ECO:0000256|ARBA:ARBA00022844};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00022595}.
SQ   SEQUENCE   73 AA;  8529 MW;  DBA89F64EF48501E CRC64;
     MDKLYTAIFG VFMGSPEDDL TDFIEIVKSV LSDEKTVTST NNTGCWGWYW LIIIFFIVLI
     LLLLIYLYLK VVW
//
DBGET integrated database retrieval system