ID Q8REF2_FUSNN Unreviewed; 711 AA.
AC Q8REF2;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Cell division protein ftsI {ECO:0000313|EMBL:AAL95351.1};
GN OrderedLocusNames=FN1155 {ECO:0000313|EMBL:AAL95351.1};
OS Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=190304 {ECO:0000313|EMBL:AAL95351.1, ECO:0000313|Proteomes:UP000002521};
RN [1] {ECO:0000313|EMBL:AAL95351.1, ECO:0000313|Proteomes:UP000002521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 /
RC KCTC 2640 / LMG 13131 / VPI 4355 {ECO:0000313|Proteomes:UP000002521};
RX PubMed=11889109; DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
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DR EMBL; AE009951; AAL95351.1; -; Genomic_DNA.
DR RefSeq; NP_604052.1; NC_003454.1.
DR AlphaFoldDB; Q8REF2; -.
DR STRING; 190304.FN1155; -.
DR PaxDb; 190304-FN1155; -.
DR EnsemblBacteria; AAL95351; AAL95351; FN1155.
DR KEGG; fnu:FN1155; -.
DR PATRIC; fig|190304.8.peg.1720; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_0_0; -.
DR InParanoid; Q8REF2; -.
DR BioCyc; FNUC190304:G1FZS-1734-MONOMER; -.
DR Proteomes; UP000002521; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IBA:GO_Central.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000313|EMBL:AAL95351.1};
KW Cell division {ECO:0000313|EMBL:AAL95351.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002521};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 652..711
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 711 AA; 80460 MW; B895CEB3587C129C CRC64;
MLFVLGVSGY LIYNKSFFLL TLFLFSIVYL VFSIAVISNW GKKQLFAKRS SIMLLIILFF
LIVYGLRLLG IQYLQKSKYV ALMNEQLLSI NKEIGQRGLI YDNKEKKLAF NNRKYTISIN
PSLLNDEKIH DEIVKDIVAI RDSKIVKLED NILEKLSKLA SEGNRYKRLV KDIDDEQKEQ
IDELLAGIER TKVKGSPKYR TVLQFEKSIE RKYYKQDEYE KLIGMVRFTE ESRDERLGIS
GLEKQYQNYL VEKRRNIPKL YGLNKKNILA LSKETLFSDL NGKNLYLTID ADLNFILNDE
IKAQFKNTNA YEAYGLIMDP NNGKILAVAA FSKDKNLLRN NIFQSQYEPG SIFKPLIVAA
AMNEKFINEN TAFNVGDGKI KRFKKTIRES SRSTRGIITA REVVMKSSNV GMVLISDYFT
NALFEDYLKA FGLYDKTGVD FPNELKPYTS SYKNWDGLKK NNMAFGQGVV ITPIQMITAF
SAVVNGGTLY KPYIVEKITD SEGTVIMRNT PTAVRKVISE EVSEKMRSIL EDTVEKGTGK
RAYIEGYAVG GKTGTAQLSA GKSGYIRNEY LSSFIGFFPA DKPKYIVMAM FMRPQADIQA
NKFGGVVAAP VVGNIIRRII KEEEGFAKNV ETINVSSSKD ENGESIKSNL DAISYEDVMP
DLEGMNPQEV LAVFKETNID IEVIGTGLVE EQRPAAGDSL KNVKKVKIIL K
//
