ID Q8RF37_FUSNN Unreviewed; 345 AA.
AC Q8RF37;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=Hemin transport system permease protein hmuU {ECO:0000313|EMBL:AAL95079.1};
GN OrderedLocusNames=FN0884 {ECO:0000313|EMBL:AAL95079.1};
OS Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=190304 {ECO:0000313|EMBL:AAL95079.1, ECO:0000313|Proteomes:UP000002521};
RN [1] {ECO:0000313|EMBL:AAL95079.1, ECO:0000313|Proteomes:UP000002521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 /
RC KCTC 2640 / LMG 13131 / VPI 4355 {ECO:0000313|Proteomes:UP000002521};
RX PubMed=11889109; DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. FecCD subfamily. {ECO:0000256|ARBA:ARBA00007935}.
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DR EMBL; AE009951; AAL95079.1; -; Genomic_DNA.
DR RefSeq; NP_603780.1; NC_003454.1.
DR RefSeq; WP_005903688.1; NZ_CP028101.1.
DR AlphaFoldDB; Q8RF37; -.
DR STRING; 190304.FN0884; -.
DR PaxDb; 190304-FN0884; -.
DR EnsemblBacteria; AAL95079; AAL95079; FN0884.
DR GeneID; 79783867; -.
DR KEGG; fnu:FN0884; -.
DR PATRIC; fig|190304.8.peg.1445; -.
DR eggNOG; COG0609; Bacteria.
DR HOGENOM; CLU_013016_0_1_0; -.
DR InParanoid; Q8RF37; -.
DR BioCyc; FNUC190304:G1FZS-1466-MONOMER; -.
DR Proteomes; UP000002521; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0033214; P:siderophore-dependent iron import into cell; IBA:GO_Central.
DR CDD; cd06550; TM_ABC_iron-siderophores_like; 1.
DR Gene3D; 1.10.3470.10; ABC transporter involved in vitamin B12 uptake, BtuC; 1.
DR InterPro; IPR037294; ABC_BtuC-like.
DR InterPro; IPR000522; ABC_transptr_permease_BtuC.
DR PANTHER; PTHR30472:SF24; FE(3+) DICITRATE TRANSPORT SYSTEM PERMEASE PROTEIN FECD-RELATED; 1.
DR PANTHER; PTHR30472; FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN; 1.
DR Pfam; PF01032; FecCD; 1.
DR SUPFAM; SSF81345; ABC transporter involved in vitamin B12 uptake, BtuC; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Iron {ECO:0000256|ARBA:ARBA00022496};
KW Iron transport {ECO:0000256|ARBA:ARBA00022496};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002521};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 345 AA; 37195 MW; CC47604534B1E9F7 CRC64;
MKKHIKNYKS LSLLLFIILI LVSTFAITVG SVSLKNLDVW KIIVNKSFNH NIFTITWEES
SEIIVWTLRA PRIVTAILAG ASLSFVGILM QALTKNPLAS PYILGISSGA STGAVLVILI
FSGSYIFISV GAFILGTLTA LLVFYFANSN GFSSTKLVLV GAAISAIFSG LTSLIIAVTP
NERAIRGALF WMSGSLAGST WQYIPFLFIS LLIVFILVYP KYDELNILVT GDENATSLGV
DVKKIRFLIM ITSTFLTGIV VANTGIIGFV GLVIPHITRG LVGGNHKKVI PIAILLGAVF
LVLTDTLTRT VVSSQEIPIG VITSVLGAPF FLSMLRRKSY RFGGE
//
