ID Q8RHT7_FUSNN Unreviewed; 195 AA.
AC Q8RHT7;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=Thymidylate synthase {ECO:0000313|EMBL:AAL94006.1};
DE EC=2.1.1.45 {ECO:0000313|EMBL:AAL94006.1};
GN OrderedLocusNames=FN1907 {ECO:0000313|EMBL:AAL94006.1};
OS Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=190304 {ECO:0000313|EMBL:AAL94006.1, ECO:0000313|Proteomes:UP000002521};
RN [1] {ECO:0000313|EMBL:AAL94006.1, ECO:0000313|Proteomes:UP000002521}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 /
RC KCTC 2640 / LMG 13131 / VPI 4355 {ECO:0000313|Proteomes:UP000002521};
RX PubMed=11889109; DOI=10.1128/JB.184.7.2005-2018.2002;
RA Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N., Overbeek R.;
RT "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT strain ATCC 25586.";
RL J. Bacteriol. 184:2005-2018(2002).
CC -!- SIMILARITY: Belongs to the IMPACT family.
CC {ECO:0000256|ARBA:ARBA00007665}.
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DR EMBL; AE009951; AAL94006.1; -; Genomic_DNA.
DR RefSeq; NP_602707.1; NC_003454.1.
DR RefSeq; WP_011015911.1; NZ_CP028101.1.
DR AlphaFoldDB; Q8RHT7; -.
DR STRING; 190304.FN1907; -.
DR PaxDb; 190304-FN1907; -.
DR EnsemblBacteria; AAL94006; AAL94006; FN1907.
DR GeneID; 79783076; -.
DR KEGG; fnu:FN1907; -.
DR PATRIC; fig|190304.8.peg.382; -.
DR eggNOG; COG1739; Bacteria.
DR HOGENOM; CLU_083552_1_1_0; -.
DR InParanoid; Q8RHT7; -.
DR BioCyc; FNUC190304:G1FZS-401-MONOMER; -.
DR Proteomes; UP000002521; Chromosome.
DR GO; GO:0004799; F:thymidylate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006446; P:regulation of translational initiation; IBA:GO_Central.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.230.30; Impact, N-terminal domain; 1.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR023582; Impact.
DR InterPro; IPR001498; Impact_N.
DR InterPro; IPR036956; Impact_N_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR015269; UPF0029_Impact_C.
DR PANTHER; PTHR16301; IMPACT-RELATED; 1.
DR PANTHER; PTHR16301:SF20; PROTEIN IMPACT; 1.
DR Pfam; PF09186; DUF1949; 1.
DR Pfam; PF01205; UPF0029; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AAL94006.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002521};
KW Transferase {ECO:0000313|EMBL:AAL94006.1}.
FT DOMAIN 18..124
FT /note="Impact N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01205"
FT DOMAIN 141..185
FT /note="UPF0029"
FT /evidence="ECO:0000259|Pfam:PF09186"
SQ SEQUENCE 195 AA; 22409 MW; F0248B94916FEC1A CRC64;
MEKIKTVKKE CKIEFEEKKS KFIGYVKPVF SKEEAEEYIK YIKNLHSDAT HNCSAYKINN
NGLEFFKVDD DGEPSGTAGK PMGDIINYME VSNLVVIATR YFGGIKLGAG GLVRNYAKTA
KLAITEAEII DFIDKIDLIF EIPYERLGEV EKLLKEYEAE VIDKSFLEKI VFKVKINKNF
YDNLENYTFI NLLDI
//
