ID HD11_ENCCU Reviewed; 138 AA.
AC Q8SWA6; Q7SI87;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2013, sequence version 2.
DT 22-FEB-2023, entry version 85.
DE RecName: Full=Homeobox protein HD-11;
DE AltName: Full=EcHD-11;
GN Name=HD-11; OrderedLocusNames=ECU02_1200;
OS Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC Encephalitozoon.
OX NCBI_TaxID=284813;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GB-M1;
RX PubMed=11719806; DOI=10.1038/35106579;
RA Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA Vivares C.P.;
RT "Genome sequence and gene compaction of the eukaryote parasite
RT Encephalitozoon cuniculi.";
RL Nature 414:450-453(2001).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=GB-M1;
RX PubMed=20003517; DOI=10.1186/1471-2164-10-607;
RA Peyretaillade E., Goncalves O., Terrat S., Dugat-Bony E., Wincker P.,
RA Cornman R.S., Evans J.D., Delbac F., Peyret P.;
RT "Identification of transcriptional signals in Encephalitozoon cuniculi
RT widespread among Microsporidia phylum: support for accurate structural
RT genome annotation.";
RL BMC Genomics 10:607-607(2009).
RN [3]
RP GENE NAME.
RX PubMed=12590353; DOI=10.1007/s00427-002-0287-3;
RA Buerglin T.R.;
RT "The homeobox genes of Encephalitozoon cuniculi (Microsporidia) reveal a
RT putative mating-type locus.";
RL Dev. Genes Evol. 213:50-52(2003).
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SEQUENCE CAUTION:
CC Sequence=DAA01305.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AL590442; CAD25149.2; -; Genomic_DNA.
DR EMBL; BK001342; DAA01305.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_584645.1; NM_001040834.1.
DR AlphaFoldDB; Q8SWA6; -.
DR SMR; Q8SWA6; -.
DR GeneID; 858635; -.
DR KEGG; ecu:ECU02_1200; -.
DR VEuPathDB; MicrosporidiaDB:ECU02_1200; -.
DR HOGENOM; CLU_128308_0_0_1; -.
DR InParanoid; Q8SWA6; -.
DR OrthoDB; 912260at2759; -.
DR Proteomes; UP000000819; Chromosome II.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 4: Predicted;
KW DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN 1..138
FT /note="Homeobox protein HD-11"
FT /id="PRO_0000048920"
FT DNA_BIND 30..89
FT /note="Homeobox"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 138 AA; 15771 MW; 4E7C3015E79027CC CRC64;
MTSERTKNLR ELEAALGLLK LSGFQMNRYC TGKQMRKTRL QTCVLNRIFE ISRFPSSKTI
VDLALLINVH PKSIQKWFQN TRQAIRKKGS TKGALLLAES EEHSAVDIPL PILADIVEIE
RRTVSKFGLE RVFLQDSN
//
