ID Q8TI44_METAC Unreviewed; 2029 AA.
AC Q8TI44;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE RecName: Full=Probable pectate lyase C {ECO:0000256|ARBA:ARBA00016512};
GN OrderedLocusNames=MA_4312 {ECO:0000313|EMBL:AAM07656.1};
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM07656.1, ECO:0000313|Proteomes:UP000002487};
RN [1] {ECO:0000313|EMBL:AAM07656.1, ECO:0000313|Proteomes:UP000002487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC {ECO:0000313|Proteomes:UP000002487};
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
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DR EMBL; AE010299; AAM07656.1; -; Genomic_DNA.
DR STRING; 188937.MA_4312; -.
DR EnsemblBacteria; AAM07656; AAM07656; MA_4312.
DR KEGG; mac:MA_4312; -.
DR HOGENOM; CLU_237670_0_0_2; -.
DR InParanoid; Q8TI44; -.
DR OrthoDB; 137924at2157; -.
DR PhylomeDB; Q8TI44; -.
DR Proteomes; UP000002487; Chromosome.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IBA:GO_Central.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006518; P:peptide metabolic process; IBA:GO_Central.
DR GO; GO:0016485; P:protein processing; IBA:GO_Central.
DR CDD; cd10276; BamB_YfgL; 1.
DR CDD; cd00146; PKD; 5.
DR Gene3D; 2.40.10.480; -; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR007742; NosD_dom.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11532:SF57; PEPTIDASE_M14 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11532; PROTEASE M14 CARBOXYPEPTIDASE; 1.
DR Pfam; PF05048; NosD; 2.
DR Pfam; PF18911; PKD_4; 5.
DR Pfam; PF13360; PQQ_2; 4.
DR SMART; SM00710; PbH1; 7.
DR SMART; SM00089; PKD; 5.
DR SMART; SM00564; PQQ; 13.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR SUPFAM; SSF49299; PKD domain; 5.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 4.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50093; PKD; 5.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Reference proteome {ECO:0000313|Proteomes:UP000002487}.
FT DOMAIN 369..446
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 455..541
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 970..1006
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 1647..1732
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 1736..1804
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 2009..2029
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 355..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2029 AA; 217763 MW; 09350272A50A6B32 CRC64;
MKKLTTVPII CIILLLMLAV APVSAKTFDI YPTDPVGTVY TIMKTQAQPG DTLFFHAGTY
TYSGVLGTMD IDVENVTWKG EGADVVLFEI SAGNPLKLKA LGCIADGFTI NISESTSVYI
TYPNCIVRDC VFKNMQGGRI SVTDSGINST VENNSFEDST SSIIMYINGV NSAKVINNEF
ESSNAGSNAA LYIRSAPMTT VADNTFKNNT KGSALMLRES TNCTVVNNTF LNDTNKVITI
YQTTAKNNII MQNNIVSSGI PIRFENAGDG NKIFLNNFAN TSGGMSGTPP AITYWNSTEP
MEYTYNGTTH TGYLGNFWGT AYTGSDGDGN GIGDISYTVP SSFGTDYAPL ISTNENYGSS
ETHETPSAPV AGFSATPTSG NAPLTVNFTD QSTNTPTSWL WDFGDNSTDT EQNPSHVYAS
AGNYTVNLTV ANADGSDSEV KTEYIVVSEP LSGAPVANFT ANVTSGTAPL TVQFTDLSSG
DGITSWAWDF DSDGTVDSNE QNPIHVYNST GTYTVSLTVT GDEGSDTETK TNYITVSETV
TESGWSQFQK DSSHTGYTFS SVPTQDPELL WQKLTSPEQE PCGSGGINVP SVISGNTVFV
TAGNASVWAF NKETGDLIWS KELGGDLTQT STPALGNGTL FVPTMEGDLY AFDPENGNEL
WKAHITDGNL ECPITYSDHK LYIGDGLEGG TGTKYYYCYD DSGNLVWQHE NANTSGFLWS
GSVVVGDYLV YPVFEGKMVC LNKDTGTFVD EVDFSKSSDV SFALTDPGMF RGSVTYADGA
LYTSSERGQE TGYCFKVGFN PDTGQFLDSG WAASIGFSTS TPVVYDGRVY VGHGEHGESG
ALFCLNDSDG TVIWETPVSG GVKSSPVISV EDGNPYIYFT EAIVDGSIYC LNPDGTLAWH
YNPPEDSAYT LQGAALSDDK VYYGTDNGYL YCIGQGEALP PEANFSSDKQ TGSFPLTVSF
KDRSFNANKF FWDFGDGNTS TEVNPVHTYT AAGSYTVTLT VENNHGEDTK VVEDYIYAVK
VPTIWPVKSG GSIQAAINSA DSGDIIKVYP GEYHEVLTID KNLTLKGIRD PVLNASGFTG
SSGITISADD VEINGFEITG TEEMCFAITV NAKNALIEDN LIDNCAEGVM FTGTGNILRQ
NNISNCWDFA AVLDSTGDNR IYQNTFINNN GRKMGGSSDH ISGGSGSFFQ SPEPVEYLWE
GEKLTGYMGN YYDDYTGNNS DGDGIGDVSY TADGGTDQYP LVMPYSYYVE EQENESIPED
SWYQFHGKVD HLGYSESGPK TNRTEWVSED IDAISSSSPV VAGGKVFVIC GAGGMEESTD
DIPQLVALDE FNGDIIWNVS IPKAVYGSWA SPAYDNGMVF TATGPELGCY DAETGEKIWC
FNDTVGSQGA VNSGPAIADG MVIFSDWDGS HYYCLDEDTG YLLWSFEVVG DGQSVPAYAD
GKFYLTSWGY GSSYAGHAYC VDAVTGEQVW HINNIEQNFC GSPAYKDGVL YLTTYNFYGD
GDLLALDAAD GSIIWQQTIQ RTDSTPAFAY GNIYVCGGCE GFSNVQTYCF NASTGEKVWE
TPSLTGEDGG IGGWTCSVAV ADGLAYVGTE GNGYFGYNDL YALDAFTGEV VWHIPHAGST
PAISEGMLFS IGADQKVYAF KDSLTSPVAN FSADITSGNA PLTVNFTDIS TGTASSYAWD
FDSDGTVDST EQNPSHTYTS AGTYTVNLTV ANAEGSDSEL KTDYITVSST PVEPEPVAAF
TADVTGGTAP LTVNFTDQST GTPTAWEWDF DNDGNVDSSE QNPSYTYNAA GNYTVNLTVE
NEAGMDFELK TDYIKVSETS GSTVTLYFDP ESSSVAENES TEINIVASNF PAGFSGYNLT
VAFDDPTVAE IVDIEYPSWA LITENSTLPG TSIYLKAVDG EDTVQAGAVD VVLATLTVSG
KEKGSANLSI GVDRLDDDSG NVIGPALLTG KIEVTLLSPL PDQEYAPKDL DGDGLYEDLT
GNGEFSFVDI VAYFHNMDWI EENMPVEYFD FNGNGRIDFD DVVDMFAMI
//
