ID Q8TLD4_METAC Unreviewed; 272 AA.
AC Q8TLD4;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE RecName: Full=Preflagellin peptidase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=MA_3102 {ECO:0000313|EMBL:AAM06475.1};
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM06475.1, ECO:0000313|Proteomes:UP000002487};
RN [1] {ECO:0000313|EMBL:AAM06475.1, ECO:0000313|Proteomes:UP000002487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC {ECO:0000313|Proteomes:UP000002487};
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
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DR EMBL; AE010299; AAM06475.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8TLD4; -.
DR STRING; 188937.MA_3102; -.
DR EnsemblBacteria; AAM06475; AAM06475; MA_3102.
DR KEGG; mac:MA_3102; -.
DR HOGENOM; CLU_086258_0_0_2; -.
DR InParanoid; Q8TLD4; -.
DR PhylomeDB; Q8TLD4; -.
DR Proteomes; UP000002487; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR Gene3D; 1.20.120.1220; -; 1.
DR Gene3D; 6.10.250.3240; -; 1.
DR InterPro; IPR009655; Preflagellin_peptidase_C.
DR InterPro; IPR000045; Prepilin_IV_endopep_pep.
DR PANTHER; PTHR36506; PREFLAGELLIN PEPTIDASE; 1.
DR PANTHER; PTHR36506:SF1; PREFLAGELLIN PEPTIDASE; 1.
DR Pfam; PF06847; Arc_PepC_II; 1.
DR Pfam; PF01478; Peptidase_A24; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002487};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..132
FT /note="Prepilin type IV endopeptidase peptidase"
FT /evidence="ECO:0000259|Pfam:PF01478"
FT DOMAIN 168..261
FT /note="Preflagellin peptidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06847"
SQ SEQUENCE 272 AA; 30625 MW; 4A528C4BF4697010 CRC64;
MPVNKMSNIH KNILNVFFMI EILKILFAMA FLLYSCYSDL KARRVSNGVW KYMLVSGSVF
VIYELFTGGT PYLKALFLSG VVVFISVYIL FHLGAFGGGD AKGLLVLSIL FPLYPIFQFS
GEAYPLLGRP LIGLFTLTVL GNALLLTALI PLGMFCYNLL HFSPEMLKKP LYMLIGYRTE
ISSLKNKEYL ALLEKFEVDE HGSIMKRFAR TGLDFDANQK PELEEYMKKG LIGKDVWVTP
GLPFMLSITA GFITAIVFGD FIFYIVMCLM LG
//
