ID Q8TMK7_METAC Unreviewed; 785 AA.
AC Q8TMK7;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Arylsulfatase {ECO:0000313|EMBL:AAM06028.1};
GN Name=atsA {ECO:0000313|EMBL:AAM06028.1};
GN OrderedLocusNames=MA_2650 {ECO:0000313|EMBL:AAM06028.1};
OS Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS C2A).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=188937 {ECO:0000313|EMBL:AAM06028.1, ECO:0000313|Proteomes:UP000002487};
RN [1] {ECO:0000313|EMBL:AAM06028.1, ECO:0000313|Proteomes:UP000002487}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A
RC {ECO:0000313|Proteomes:UP000002487};
RX PubMed=11932238; DOI=10.1101/gr.223902;
RA Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA Cann I., Graham D.E., Grahame D.A., Guss A., Hedderich R., Ingram-Smith C.,
RA Kuettner C.H., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B.,
RA Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H.,
RA de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L.,
RA Paulsen I., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H.,
RA Lander E., Metcalf W.W., Birren B.;
RT "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT physiological diversity.";
RL Genome Res. 12:532-542(2002).
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; AE010299; AAM06028.1; -; Genomic_DNA.
DR RefSeq; WP_011022610.1; NC_003552.1.
DR AlphaFoldDB; Q8TMK7; -.
DR STRING; 188937.MA_2650; -.
DR EnsemblBacteria; AAM06028; AAM06028; MA_2650.
DR GeneID; 1474539; -.
DR KEGG; mac:MA_2650; -.
DR HOGENOM; CLU_006332_11_0_2; -.
DR InParanoid; Q8TMK7; -.
DR OrthoDB; 3164at2157; -.
DR PhylomeDB; Q8TMK7; -.
DR Proteomes; UP000002487; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd16025; PAS_like; 1.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR PANTHER; PTHR42693:SF43; BLL2667 PROTEIN; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00149; SULFATASE_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000002487}.
FT DOMAIN 37..448
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 785 AA; 88601 MW; 7ABBB504B9193421 CRC64;
MIEYEPGKPF PGVIGRTLDE SSPAWPRPTR AGESAANVIF FILDDVGYGQ MSVFGGLCET
PNLERLANRG LRYTNMQTTA LCSPTRGCAL TGRNHHTLGL SAITELSMGY PAHNGYMGFE
HGFLSEILLE QGYNTFAVGK WHLTPPEETT TAGPFHRWPL GRGFERYYGF LGGNTDQWHP
DLTYDNHPVP VPATPEEGYH LNIDLADKAI EFIKDAHHNA PDKPFFLYYA TGAGHAPRHV
EKKWIEKYKG RFDMGWDKYR KTVFKHQKGL GIVPPDALLS ERDPDVPAWD SLTDTEKKVY
ARQMEVFAAF IEQTDYHFGR ILDFLEEIGE LDNTLVIVLS DNGASAEGGI HGTFNEMLFF
NNVEETLEDN LERIEKWGNP ETFNHYSWGW TWAGDTPFRR WKRETYRGGI SDACIVSWPE
GVKARGENRS QYAHAIDLVP TVLEALGMEA PKNIRGVSQS PIQGVSFAHT FDDPGAPTKH
ITQYFEMFGH RSIYNDGWRA VCPFPGSSFA EPLREGWFFG MPLSSRVLKV LDSKGWELYE
LAEDPAEIRN LAKEKPEKLQ EMIQRWYTEA GKYGVLPLAT AALERMNVQR PTIARPRTKY
IYYAGGTPVQ FSAAPRVYNR PWSITARVVI PEEGAEGVLL AHGNRHGGYS FYVKDGHLHH
VHNYSGLEKF RISSPDPIPK GEVTLRYEFE KTDEPDFSKG KGSAGRSQLY INGELVASRN
LPYTVPNLFG IIGLSCGYDA ADSVHPEEYR APFTFTGRIR QVELDVSGEL IKDEEADLKR
MMTEQ
//
