ID Q8TYZ8_METKA Unreviewed; 252 AA.
AC Q8TYZ8;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Probable membrane transporter protein {ECO:0000256|RuleBase:RU363041};
GN OrderedLocusNames=MK0143 {ECO:0000313|EMBL:AAM01360.1};
OS Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC Archaea; Euryarchaeota; Methanomada group; Methanopyri; Methanopyrales;
OC Methanopyraceae; Methanopyrus.
OX NCBI_TaxID=190192 {ECO:0000313|EMBL:AAM01360.1, ECO:0000313|Proteomes:UP000001826};
RN [1] {ECO:0000313|EMBL:AAM01360.1, ECO:0000313|Proteomes:UP000001826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938
RC {ECO:0000313|Proteomes:UP000001826};
RX PubMed=11930014; DOI=10.1073/pnas.032671499;
RA Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA Koonin E.V., Kozyavkin S.A.;
RT "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT monophyly of archaeal methanogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363041};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363041}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the 4-toluene sulfonate uptake permease (TSUP)
CC (TC 2.A.102) family. {ECO:0000256|RuleBase:RU363041}.
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DR EMBL; AE009439; AAM01360.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8TYZ8; -.
DR STRING; 190192.MK0143; -.
DR PaxDb; 190192-MK0143; -.
DR EnsemblBacteria; AAM01360; AAM01360; MK0143.
DR KEGG; mka:MK0143; -.
DR HOGENOM; CLU_045498_5_4_2; -.
DR InParanoid; Q8TYZ8; -.
DR OrthoDB; 57092at2157; -.
DR Proteomes; UP000001826; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002781; TM_pro_TauE-like.
DR PANTHER; PTHR43701; MEMBRANE TRANSPORTER PROTEIN MJ0441-RELATED; 1.
DR PANTHER; PTHR43701:SF2; MEMBRANE TRANSPORTER PROTEIN MJ0441-RELATED; 1.
DR Pfam; PF01925; TauE; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363041};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363041};
KW Reference proteome {ECO:0000313|Proteomes:UP000001826};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363041};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363041}.
FT TRANSMEM 6..33
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363041"
FT TRANSMEM 45..63
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363041"
FT TRANSMEM 75..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363041"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363041"
FT TRANSMEM 171..194
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363041"
FT TRANSMEM 200..220
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363041"
FT TRANSMEM 232..251
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363041"
SQ SEQUENCE 252 AA; 25674 MW; F82AF8B979129DFF CRC64;
MIPDPSMMLY LGIGGLVGLV SGMFGVGGGF LLVPLLNSTG MPMHLALGTT LLAISLGGFT
GAYRHLQEGN VHVDAAPIFG LSAIVGAQVG SYLACLTPEH VLKVALGVAC SAMALRMAFD
GETEEGNEIR DNIAVASLTG FGVGAFSGFT GSGGGVLFVP VMASVLNFPT MLAIGTSSVI
VPVSALAGAA QYWMEGYVNF WAALAVVTGM LISSYVGAEL SNKIGGERVK RAFSVVLALV
GAKMVLSGLR LV
//
