ID Q8U096_PYRFU Unreviewed; 148 AA.
AC Q8U096;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:AAL81827.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:AAL81827.1};
GN OrderedLocusNames=PF1703 {ECO:0000313|EMBL:AAL81827.1};
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497 {ECO:0000313|EMBL:AAL81827.1, ECO:0000313|Proteomes:UP000001013};
RN [1] {ECO:0000313|EMBL:AAL81827.1, ECO:0000313|Proteomes:UP000001013}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1
RC {ECO:0000313|Proteomes:UP000001013};
RX PubMed=10430560;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
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DR EMBL; AE009950; AAL81827.1; -; Genomic_DNA.
DR RefSeq; WP_011012849.1; NZ_CP023154.1.
DR AlphaFoldDB; Q8U096; -.
DR STRING; 186497.PF1703; -.
DR PaxDb; 186497-PF1703; -.
DR GeneID; 80427286; -.
DR KEGG; pfu:PF1703; -.
DR PATRIC; fig|186497.12.peg.1771; -.
DR eggNOG; arCOG00245; Archaea.
DR HOGENOM; CLU_1754776_0_0_2; -.
DR OrthoDB; 24743at2157; -.
DR PhylomeDB; Q8U096; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046826; PDH_N.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:AAL81827.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001013}.
FT DOMAIN 43..131
FT /note="Prephenate dehydrogenase nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02153"
SQ SEQUENCE 148 AA; 17022 MW; 399297E7EE019F9E CRC64;
MRITISGYGK MGKLFGRVLS EELNSEVKFY SSHTILDFST LSEAYEWSDV MILASTIDNI
KAQIRELREI SLSNPKDIMI FDIATFKKDV LTEYQGFPRE VKVASVHPMF GPGAKSFRGH
LFYRCPCKGQ GKRRRRCRKV YRRIGGKS
//
