ID Q8U3C3_PYRFU Unreviewed; 448 AA.
AC Q8U3C3;
DT 01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2002, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=CobW/HypB/UreG nucleotide-binding domain-containing protein {ECO:0000259|Pfam:PF02492};
GN OrderedLocusNames=PF0547 {ECO:0000313|EMBL:AAL80671.1};
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497 {ECO:0000313|EMBL:AAL80671.1, ECO:0000313|Proteomes:UP000001013};
RN [1] {ECO:0000313|EMBL:AAL80671.1, ECO:0000313|Proteomes:UP000001013}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1
RC {ECO:0000313|Proteomes:UP000001013};
RX PubMed=10430560;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
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DR EMBL; AE009950; AAL80671.1; -; Genomic_DNA.
DR RefSeq; WP_011011665.1; NZ_CP023154.1.
DR AlphaFoldDB; Q8U3C3; -.
DR IntAct; Q8U3C3; 1.
DR STRING; 186497.PF0547; -.
DR PaxDb; 186497-PF0547; -.
DR GeneID; 41712352; -.
DR KEGG; pfu:PF0547; -.
DR PATRIC; fig|186497.12.peg.575; -.
DR eggNOG; arCOG01229; Archaea.
DR HOGENOM; CLU_046378_0_0_2; -.
DR OrthoDB; 14509at2157; -.
DR PhylomeDB; Q8U3C3; -.
DR Proteomes; UP000001013; Chromosome.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42869; SLL0572 PROTEIN; 1.
DR PANTHER; PTHR42869:SF1; SLL0572 PROTEIN; 1.
DR Pfam; PF02492; cobW; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001013}.
FT DOMAIN 239..299
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
SQ SEQUENCE 448 AA; 50756 MW; FB154F1722F57C8F CRC64;
MAEKKRRRVV ILGAAGRDFH NFNVFFRDNP DYEVVAFTAT QIPDIEGRIY PPELAGELYP
NGIPILPEDD LEKIIKEHDV DIVVFAYSDV SHEHVMHLAS RAHSAGADFW LLGPKSTMLK
SSKPVVAVTA VRTGCGKSQT SRKVAQILQE MGFKVVAVRH PMPYGDLRKQ VVQRFATFED
LDRYECTIEE REEYEPYLER GMVVYAGVDY EKILREAEKE ADIILWDGGN NDFPFFEPDL
WIVVTDPHRP GHELTHHPGE TNFRSADVII INKIDTAPPE NIQKIRENIE KINPNAIVIE
AASPIFVDKP ELIKGKRVLV VEDGPTLTHG GMSFGAGYIA AKKFGAKEIV DPRPYAVGSI
IETYKKYPHL SNILPAMGYG KKQIKELEET INRADADVVV MGTPVDLRRF MNLNKPAVRV
KYELEEIGKP KLRDVLEEWV KKCEKLKK
//
