ID ZWIP4_ARATH Reviewed; 412 AA.
AC Q8W030; Q9LT33;
DT 26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 24-JAN-2024, entry version 148.
DE RecName: Full=Zinc finger protein WIP4;
DE AltName: Full=WIP-domain protein 4 {ECO:0000303|PubMed:11782451};
DE Short=AtWIP4 {ECO:0000303|PubMed:11782451};
GN Name=WIP4 {ECO:0000303|PubMed:11782451};
GN OrderedLocusNames=At3g20880 {ECO:0000312|Araport:AT3G20880};
GN ORFNames=MOE17.19 {ECO:0000312|EMBL:BAB02496.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11782451; DOI=10.1101/gad.212702;
RA Sagasser M., Lu G.-H., Hahlbrock K., Weisshaar B.;
RT "A. thaliana TRANSPARENT TESTA 1 is involved in seed coat development and
RT defines the WIP subfamily of plant zinc finger proteins.";
RL Genes Dev. 16:138-149(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP SUBCELLULAR LOCATION, AND ZINC-FINGER.
RX PubMed=20541552; DOI=10.1016/j.febslet.2010.06.007;
RA Appelhagen I., Huep G., Lu G.H., Strompen G., Weisshaar B., Sagasser M.;
RT "Weird fingers: functional analysis of WIP domain proteins.";
RL FEBS Lett. 584:3116-3122(2010).
CC -!- FUNCTION: Probable transcriptional regulator.
CC {ECO:0000305|PubMed:20541552}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20541552}.
CC -!- SIMILARITY: Belongs to the WIP C2H2-type zinc-finger protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02496.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AJ311811; CAC86168.1; -; mRNA.
DR EMBL; AB025629; BAB02496.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE76435.1; -; Genomic_DNA.
DR RefSeq; NP_188724.2; NM_112980.3.
DR AlphaFoldDB; Q8W030; -.
DR STRING; 3702.Q8W030; -.
DR PaxDb; 3702-AT3G20880-1; -.
DR EnsemblPlants; AT3G20880.1; AT3G20880.1; AT3G20880.
DR GeneID; 821637; -.
DR Gramene; AT3G20880.1; AT3G20880.1; AT3G20880.
DR KEGG; ath:AT3G20880; -.
DR Araport; AT3G20880; -.
DR TAIR; AT3G20880; WIP4.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_052255_0_1_1; -.
DR InParanoid; Q8W030; -.
DR OMA; PIHKHQE; -.
DR OrthoDB; 3035250at2759; -.
DR PhylomeDB; Q8W030; -.
DR PRO; PR:Q8W030; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8W030; baseline and differential.
DR Genevisible; Q8W030; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0080022; P:primary root development; IGI:TAIR.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; TAS:TAIR.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR043584; WIP1/2/3/4/5/6.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45878; ZINC FINGER PROTEIN WIP2; 1.
DR PANTHER; PTHR45878:SF12; ZINC FINGER PROTEIN WIP4; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..412
FT /note="Zinc finger protein WIP4"
FT /id="PRO_0000431318"
FT ZN_FING 256..278
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 303..335
FT /note="C2H2-type 2; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT ZN_FING 340..362
FT /note="C2H2-type 3; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT ZN_FING 366..391
FT /note="C2H2-type 4; atypical"
FT /evidence="ECO:0000303|PubMed:20541552"
FT REGION 187..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 332..335
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250|UniProtKB:Q8VWG3"
FT MOTIF 375..378
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250|UniProtKB:Q8VWG3"
SQ SEQUENCE 412 AA; 47155 MW; EFB2DD98E068895A CRC64;
MLFSTVLSHR TLYILTCPNT LIHSYTHPHI HAYLAFTGFL TQLHHLEISC LLLLFFSLSS
LLKLMADPDC IFRNGYVDYY NYSFNYATSL SRIYNSHDSF YYPHQTTNPN INENPNLTSP
DSPPLREALP LLSLSPIHKH QEPTANHHEY YFMETTETSS NSNFLDQCQD SYRHDVTVDL
HLGLPNLGDG GSSSSDVVLD STDHQEGHHD HHQDQGLEVT MASDHDDEHG GLQRGNHLHH
FWIPTPSQIL MGPTQFSCPL CFKTFNRYNN MQMHMWGHGS QYRKGPESLR GTQPTAMLKL
PCYCCAPGCK NNIDHPRARP LKDFRTLQTH YKRKHGVRPF ACRRCGKAFA VKGDWRTHEK
NCGKLWYCSC GSDFKHKRSL KDHVKAFGNG HVPCCGIDHE EEEAASDVEQ QE
//
