ID Q8WN71_CANLF Unreviewed; 166 AA.
AC Q8WN71;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 133.
DE RecName: Full=Myosin regulatory light chain 2, ventricular/cardiac muscle isoform {ECO:0000256|ARBA:ARBA00039646};
DE AltName: Full=Myosin light chain 2, slow skeletal/ventricular muscle isoform {ECO:0000256|ARBA:ARBA00042617};
GN Name=MYL2 {ECO:0000313|Ensembl:ENSCAFP00845039656.1};
OS Canis lupus familiaris (Dog) (Canis familiaris).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX NCBI_TaxID=9615 {ECO:0000313|EMBL:AAL37760.1};
RN [1] {ECO:0000313|EMBL:AAL37760.1}
RP NUCLEOTIDE SEQUENCE.
RA Depre C., Tomlinson J.E., Thompson E.;
RT "Canine ventricular myosin light chain 2.";
RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCAFP00845039656.1}
RP IDENTIFICATION.
RC STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00845039656.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, myofibril, sarcomere, A band
CC {ECO:0000256|ARBA:ARBA00004161}.
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DR EMBL; AF440218; AAL37760.1; -; mRNA.
DR RefSeq; NP_001003069.1; NM_001003069.1.
DR Ensembl; ENSCAFT00845050581.1; ENSCAFP00845039656.1; ENSCAFG00845028634.1.
DR GeneID; 403614; -.
DR KEGG; cfa:403614; -.
DR CTD; 4633; -.
DR VEuPathDB; HostDB:ENSCAFG00845028634; -.
DR eggNOG; KOG0031; Eukaryota.
DR GeneTree; ENSGT00940000155578; -.
DR HOGENOM; CLU_061288_9_0_1; -.
DR OMA; CKEETLR; -.
DR OrthoDB; 312751at2759; -.
DR TreeFam; TF314218; -.
DR Proteomes; UP000805418; Chromosome 26.
DR GO; GO:0031672; C:A band; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23049; MYOSIN REGULATORY LIGHT CHAIN 2; 1.
DR PANTHER; PTHR23049:SF9; MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR_CARDIAC MUSCLE ISOFORM; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 2: Evidence at transcript level;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000805418};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 24..59
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 94..129
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 166 AA; 18903 MW; 75335EA891777249 CRC64;
MAPKKAKKRA EGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR DTFAALGRVN
VKNEEIDEML KEAPGPINFT VFLTMFGEKL KGADPEETIL NAFKVFDPEG KGVLRADYVR
EMLTTQAERF SKEEIDQMFA AFPPDVTGNL DYKNLVHIIT HGEEKD
//
