ID Q8XCV7_ECO57 Unreviewed; 555 AA.
AC Q8XCV7; A0A0H3JDW5; A0A6M0JMF8; Q7AGU6;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 137.
DE SubName: Full=NAD(P)-binding acyl-CoA synthetase {ECO:0000313|EMBL:BAB34003.1};
GN Name=fdrA {ECO:0000313|EMBL:BAB34003.1};
GN ORFNames=ECs_0580 {ECO:0000313|EMBL:BAB34003.1};
OS Escherichia coli O157:H7.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334 {ECO:0000313|EMBL:BAB34003.1, ECO:0000313|Proteomes:UP000000558};
RN [1] {ECO:0000313|EMBL:BAB34003.1, ECO:0000313|Proteomes:UP000000558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC {ECO:0000313|Proteomes:UP000000558};
RX PubMed=11258796; DOI=.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
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DR EMBL; BA000007; BAB34003.1; -; Genomic_DNA.
DR RefSeq; NP_308607.1; NC_002695.1.
DR RefSeq; WP_000580831.1; NZ_VOAI01000030.1.
DR AlphaFoldDB; Q8XCV7; -.
DR STRING; 155864.Z0673; -.
DR GeneID; 916573; -.
DR KEGG; ecs:ECs_0580; -.
DR PATRIC; fig|386585.9.peg.687; -.
DR eggNOG; COG0074; Bacteria.
DR HOGENOM; CLU_026233_1_0_6; -.
DR OMA; HPMIDYS; -.
DR Proteomes; UP000000558; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR005811; SUCC_ACL_C.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR11117:SF2; SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11117; SUCCINYL-COA LIGASE SUBUNIT ALPHA; 1.
DR Pfam; PF02629; CoA_binding; 1.
DR Pfam; PF00549; Ligase_CoA; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000558}.
FT DOMAIN 193..287
FT /note="CoA-binding"
FT /evidence="ECO:0000259|Pfam:PF02629"
FT DOMAIN 336..491
FT /note="ATP-citrate synthase/succinyl-CoA ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00549"
SQ SEQUENCE 555 AA; 58581 MW; 27F1E3670EA45438 CRC64;
MIHAFIKKGC FQDSVSLMII SRKLSESENV DDVSVMMGTP ANKALLDTTG FWHDDFNNAT
PNDICVAIRS EAADAGIAQA IMQQLEEALK QLAQGSGSSQ ALTQVRRWDS ACQKLPDANL
ALISVAGEYA AELANQALDR NLNVMMFSDN VTLEDEIQLK TRAREKGLLV MGPDCGTSMI
AGTPLAFANV MPEGNIGVIG ASGTGIQELC SQIALAGEGI THAIGLGGRD LSREVGGISA
LTALEMLSAD EKSEVLAFVS KPPAEAVRLK IVNAMKATGK PTVALFLGYT PAVARDENVW
FASSLDEAAR LACLLSRVTA RRNAIMPASS GFICGLYTGG TLAAEAAGLL AGHLGVEADD
AHHHGMMLDA DGHQIIDLGD DFYTVGRPHP MIDPTLRNQL ITDLGAKPQV RVLLLDVVIG
FGATADPAAS LVSAWQKACA ARSDNQPLYA IATVTGTERD PQCRSQQIAT LEDAGIAVVS
SLPEATLLAA ALIHPLSPAA QQHTPSLLEN VAVINIGLRS FALELQSASK PVVHYQWSPV
AGGNKKLARL LERLQ
//
