ID Q8XDK7_ECO57 Unreviewed; 466 AA.
AC Q8XDK7; A0A0H3JL65; A0A6M0JF19; Q7A9W6;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE SubName: Full=Permease {ECO:0000313|EMBL:BAB37881.1};
GN ORFNames=ECs_4458 {ECO:0000313|EMBL:BAB37881.1};
OS Escherichia coli O157:H7.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334 {ECO:0000313|EMBL:BAB37881.1, ECO:0000313|Proteomes:UP000000558};
RN [1] {ECO:0000313|EMBL:BAB37881.1, ECO:0000313|Proteomes:UP000000558}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC
RC {ECO:0000313|Proteomes:UP000000558};
RX PubMed=11258796; DOI=.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000256|ARBA:ARBA00009617}.
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DR EMBL; BA000007; BAB37881.1; -; Genomic_DNA.
DR RefSeq; NP_312485.1; NC_002695.1.
DR RefSeq; WP_000204825.1; NZ_VOAI01000004.1.
DR AlphaFoldDB; Q8XDK7; -.
DR STRING; 155864.Z5001; -.
DR GeneID; 915602; -.
DR KEGG; ecs:ECs_4458; -.
DR PATRIC; fig|386585.9.peg.4668; -.
DR eggNOG; COG2211; Bacteria.
DR HOGENOM; CLU_027408_0_2_6; -.
DR OMA; MAIRFCK; -.
DR Proteomes; UP000000558; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd17332; MFS_MelB_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001927; Na/Gal_symport.
DR NCBIfam; TIGR00792; gph; 1.
DR PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000000558};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ SEQUENCE 466 AA; 51387 MW; 4F416EBD33643A53 CRC64;
MTSTPITTAD IAKGKIDDAL SVREKIGYGL GDAGGTVITC LIMNFLTFFY TDVFGLTPAL
VGTLFIALRV FDAISDPVMG VIADRTQSRW GRFRPWQLWI AIPIGIIGIL TFTVPDASMG
VKIAWAFGTY LLLSVGYTAI NVPYCARINT MTTRHNEVIS CQSWRFVLCG VAGFLVSVGL
PWMVALFGQG NAARGYQLGV GVLCAIAVVM FLCCFFWVRE RVPLSTMGKF TLREHLAGLR
NNDQLLLMLV MSFLLINVFN IRGGGYMYFI TYVLQGSTGY TSLFFTMVTF ASIIGSVIVS
PLTRRFDTVK IYYYTNLLLA ALAVLMWFLP SGPAYQTLWL AVILGNGVIL GFTLPLHFSL
MAFADDYGEW KTHVRSSGMN FAFNLFFIKL AWASSAGIIS LLFIFVAYQP GVENQTASSL
GGIAAMETLL PALFHLLLAG AIRFCKLNNP MMSRIATDLR QRHVQP
//
