ID Q8XL15_CLOPE Unreviewed; 209 AA.
AC Q8XL15;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Precorrin isomerase {ECO:0000313|EMBL:BAB80933.1};
GN Name=cbiC {ECO:0000313|EMBL:BAB80933.1};
OS Clostridium perfringens (strain 13 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=195102 {ECO:0000313|EMBL:BAB80933.1, ECO:0000313|Proteomes:UP000000818};
RN [1] {ECO:0000313|EMBL:BAB80933.1, ECO:0000313|Proteomes:UP000000818}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13 / Type A {ECO:0000313|Proteomes:UP000000818};
RX PubMed=11792842; DOI=10.1073/pnas.022493799;
RA Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT eater.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BA000016; BAB80933.1; -; Genomic_DNA.
DR RefSeq; WP_003452122.1; NC_003366.1.
DR AlphaFoldDB; Q8XL15; -.
DR STRING; 195102.gene:10490490; -.
DR GeneID; 69449129; -.
DR KEGG; cpe:CPE1227; -.
DR HOGENOM; CLU_084703_1_1_9; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000000818; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:BAB80933.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000818}.
FT DOMAIN 10..203
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 209 AA; 23100 MW; 18A4E25A289E68D9 CRC64;
MDYMKSPMGI EKRSFEIIGS EMHEHNFSEE ELQIVKRVIH TTADFEYQDL IEISEGAIEA
GVSALKNGAK IYTDTTMALS GMNKRALKEL NASVECYVGL EEVFKLAKEK EITRSMAGVE
LAAKENVDIF VFGNAPTALF KLRELIKEGK ANPKLIVAVP VGFVGASESK EDLDELGIPY
IRVKGRKGGS TVAAAIINAL LYMNYKRDM
//
