ID Q8XNI2_CLOPE Unreviewed; 487 AA.
AC Q8XNI2;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Probable penicillin-binding protein {ECO:0000313|EMBL:BAB80057.1};
GN OrderedLocusNames=CPE0351 {ECO:0000313|EMBL:BAB80057.1};
OS Clostridium perfringens (strain 13 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=195102 {ECO:0000313|EMBL:BAB80057.1, ECO:0000313|Proteomes:UP000000818};
RN [1] {ECO:0000313|EMBL:BAB80057.1, ECO:0000313|Proteomes:UP000000818}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13 / Type A {ECO:0000313|Proteomes:UP000000818};
RX PubMed=11792842; DOI=10.1073/pnas.022493799;
RA Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT eater.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
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DR EMBL; BA000016; BAB80057.1; -; Genomic_DNA.
DR RefSeq; WP_003452191.1; NC_003366.1.
DR AlphaFoldDB; Q8XNI2; -.
DR SMR; Q8XNI2; -.
DR STRING; 195102.gene:10489607; -.
DR GeneID; 69448110; -.
DR KEGG; cpe:CPE0351; -.
DR HOGENOM; CLU_009289_1_0_9; -.
DR Proteomes; UP000000818; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000818};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 170..482
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 487 AA; 52468 MW; 9666DB53DD65AC80 CRC64;
MAKKKDLSGS IKKVMFVYLV LLVGLISYIA YFQLIQVPKI AEMDSNSAVM AAQNEVIRGE
IKDRDGNVLA KSTKSGDLTQ KREYPYGEIY SHPIGYASGI YGNAGLEGAY SKELTTYENV
SLKAFLKSFN LKKDFKERNE SDKKVGNSIV TTLDTDLQKA AYAALGANRG AVVALDPKTG
AVLASVSKPG FNPNNMKETY EIANNPNGNP KDAILVDRAL NGQYPPGSTF KVVTLTSALE
NLPGVTERTF NDTGSINVGT KDLPNENGNA YGNISLRKAL SVSSNVIFGG ILGEELGNKK
LRETAEKYGF NKDLYLGNLK AYSGSFPDRK TVDKGLIAYD AIGQGEVLSS PIEMAMVAAT
VANNGVRMEP YIVSKVVDKD GDTVKEFSST KKDTVMSKEQ AQIINEYMQG VAKDRINDNW
GYFKGMNVAA KTGTAQVPDG NSHAWLIAFA PADDPKIAVA TIVENGGSGS KVAAPVTARV
MQAYFNK
//
