ID TAGH_LISMO Reviewed; 333 AA.
AC Q8Y843;
DT 29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 124.
DE RecName: Full=Teichoic acids export ATP-binding protein TagH {ECO:0000255|HAMAP-Rule:MF_01715};
DE EC=7.5.2.4 {ECO:0000255|HAMAP-Rule:MF_01715};
GN Name=tagH {ECO:0000255|HAMAP-Rule:MF_01715}; OrderedLocusNames=lmo1075;
OS Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=169963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-679 / EGD-e;
RX PubMed=11679669; DOI=10.1126/science.1063447;
RA Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT "Comparative genomics of Listeria species.";
RL Science 294:849-852(2001).
CC -!- FUNCTION: Part of the ABC transporter complex TagGH involved in
CC teichoic acids export. Responsible for energy coupling to the transport
CC system. {ECO:0000255|HAMAP-Rule:MF_01715}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + teichoic acidSide 1 = ADP + phosphate + teichoic
CC acidSide 2.; EC=7.5.2.4; Evidence={ECO:0000255|HAMAP-Rule:MF_01715};
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (TagH) and
CC two transmembrane proteins (TagG). {ECO:0000255|HAMAP-Rule:MF_01715}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01715};
CC Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01715}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Teichoic acids
CC exporter (TC 3.A.1.104.1) family. {ECO:0000255|HAMAP-Rule:MF_01715}.
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DR EMBL; AL591977; CAC99153.1; -; Genomic_DNA.
DR PIR; AC1209; AC1209.
DR RefSeq; NP_464600.1; NC_003210.1.
DR RefSeq; WP_003722702.1; NZ_CP023861.1.
DR AlphaFoldDB; Q8Y843; -.
DR SMR; Q8Y843; -.
DR STRING; 169963.gene:17593731; -.
DR PaxDb; 169963-lmo1075; -.
DR EnsemblBacteria; CAC99153; CAC99153; CAC99153.
DR GeneID; 986506; -.
DR KEGG; lmo:lmo1075; -.
DR PATRIC; fig|169963.11.peg.1105; -.
DR eggNOG; COG1134; Bacteria.
DR HOGENOM; CLU_000604_1_2_9; -.
DR OrthoDB; 9778870at2; -.
DR PhylomeDB; Q8Y843; -.
DR BioCyc; LMON169963:LMO1075-MONOMER; -.
DR Proteomes; UP000000817; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015438; F:ABC-type teichoic acid transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03220; ABC_KpsT_Wzt; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR015860; ABC_transpr_TagH-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46743; TEICHOIC ACIDS EXPORT ATP-BINDING PROTEIN TAGH; 1.
DR PANTHER; PTHR46743:SF2; TEICHOIC ACIDS EXPORT ATP-BINDING PROTEIN TAGH; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS51251; TAGH; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW Reference proteome; Translocase; Transport.
FT CHAIN 1..333
FT /note="Teichoic acids export ATP-binding protein TagH"
FT /id="PRO_0000092994"
FT DOMAIN 26..246
FT /note="ABC transporter"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01715"
FT BINDING 60..67
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01715"
SQ SEQUENCE 333 AA; 37338 MW; D58D8253A417437E CRC64;
MDKNIKVSFK HVSKEYDLYQ NKSDKIKGLF LPKSKRVQSF WALRNVCFDV YDGETVGLIG
INGSGKSTIS NIMSGVIPPT QGEVVINGET SLIAIAVGLK GPLSGLENIR LKLLMHGLKG
SQIDSLLPSI IEFADIGDFI NQPIKNYSSG MRSRLGFAIS VHTDPDILVV DEALSVGDQT
FYQKCVDKIN EFKAQGKTIV FVSHSLGQVK SLCDKIIWMH HGEVREIGDA AEVAEKYDEF
VKWFNKQPND FKKKYQKEQK EKQKLPQEKI YPTPNANKYK MGLFDKCFLV VLLALLVLFG
SLISTGKSFM GLFSATDNKV EQVTKVDKRT DWK
//
