ID Q8Y8Y9_LISMO Unreviewed; 226 AA.
AC Q8Y8Y9;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 141.
DE SubName: Full=Lmo0753 protein {ECO:0000313|EMBL:CAC98831.1};
GN OrderedLocusNames=lmo0753 {ECO:0000313|EMBL:CAC98831.1};
OS Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=169963 {ECO:0000313|EMBL:CAC98831.1, ECO:0000313|Proteomes:UP000000817};
RN [1] {ECO:0000313|EMBL:CAC98831.1, ECO:0000313|Proteomes:UP000000817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-679 / EGD-e {ECO:0000313|Proteomes:UP000000817};
RX PubMed=11679669; DOI=10.1126/science.1063447;
RA Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.D.,
RA Fsihi H., Portillo F.G., Garrido P., Gautier L., Goebel W., Gomez-Lopez N.,
RA Hain T., Hauf J., Jackson D., Jones L.M., Kaerst U., Kreft J., Kuhn M.,
RA Kunst F., Kurapkat G., Madueno E., Maitournam A., Vicente J.M., Ng E.,
RA Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.C.,
RA Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A.,
RA Vazquez-Boland J.A., Voss H., Wehland J., Cossart P.;
RT "Comparative genomics of Listeria species.";
RL Science 294:849-852(2001).
RN [2] {ECO:0007829|PDB:7T8O}
RP X-RAY CRYSTALLOGRAPHY (2.71 ANGSTROMS).
RG Center for Structural Genomics of Infectious Diseases (CSGID);
RA Kim Y., Makowska-Grzyska M., Maltseva N., Shatsman S., Joachimiak A.;
RT "Crystal Structure of the Crp/Fnr Family Transcriptional Regulator from
RT Listeria monocytogenes.";
RL Submitted (DEC-2021) to the PDB data bank.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL591976; CAC98831.1; -; Genomic_DNA.
DR PIR; AI1168; AI1168.
DR RefSeq; NP_464280.1; NC_003210.1.
DR RefSeq; WP_003721870.1; NZ_CP023861.1.
DR PDB; 7T8O; X-ray; 2.71 A; A/B=1-226.
DR AlphaFoldDB; Q8Y8Y9; -.
DR SMR; Q8Y8Y9; -.
DR STRING; 169963.gene:17593404; -.
DR PaxDb; 169963-lmo0753; -.
DR EnsemblBacteria; CAC98831; CAC98831; CAC98831.
DR GeneID; 985518; -.
DR KEGG; lmo:lmo0753; -.
DR PATRIC; fig|169963.11.peg.776; -.
DR eggNOG; COG0664; Bacteria.
DR HOGENOM; CLU_075053_4_1_9; -.
DR OrthoDB; 3176638at2; -.
DR PhylomeDB; Q8Y8Y9; -.
DR BioCyc; LMON169963:LMO0753-MONOMER; -.
DR Proteomes; UP000000817; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR012318; HTH_CRP.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF13545; HTH_Crp_2; 1.
DR SMART; SM00419; HTH_CRP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS51063; HTH_CRP_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:7T8O};
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000000817}.
FT DOMAIN 12..93
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 153..219
FT /note="HTH crp-type"
FT /evidence="ECO:0000259|PROSITE:PS51063"
SQ SEQUENCE 226 AA; 25717 MW; 9DA758CAB7132757 CRC64;
MNIRTELQNS QLCEGITEAQ LTELMNKITV KEKHYKNNEI LFYTDEVTKV YILVKGNAAI
AKNTSSGKRI LGKNVTEPGE LAGEIYYFSH RNPFWDYAIV LEPTTVLEIS GIDQGTLQTL
DLALQNQLLV NLLKSVTRKF EYIGEKVRMV SEDSVRAKIS NYLFGIQDDD GSIELTETRE
EIADYLDITR PSLSRELGRM QKENIIRIEG SSVIILDAII FDTFIE
//
