ID Q8YRK3_NOSS1 Unreviewed; 714 AA.
AC Q8YRK3;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE RecName: Full=aminodeoxychorismate synthase {ECO:0000256|ARBA:ARBA00013139};
DE EC=2.6.1.85 {ECO:0000256|ARBA:ARBA00013139};
GN OrderedLocusNames=alr3443 {ECO:0000313|EMBL:BAB75142.1};
OS Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=103690 {ECO:0000313|EMBL:BAB75142.1, ECO:0000313|Proteomes:UP000002483};
RN [1] {ECO:0000313|EMBL:BAB75142.1, ECO:0000313|Proteomes:UP000002483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576
RC {ECO:0000313|Proteomes:UP000002483};
RX PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT "Complete genomic sequence of the filamentous nitrogen-fixing
RT cyanobacterium Anabaena sp. strain PCC 7120.";
RL DNA Res. 8:205-213(2001).
CC -!- SIMILARITY: In the C-terminal section; belongs to the anthranilate
CC synthase component I family. {ECO:0000256|ARBA:ARBA00005970}.
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DR EMBL; BA000019; BAB75142.1; -; Genomic_DNA.
DR PIR; AD2236; AD2236.
DR AlphaFoldDB; Q8YRK3; -.
DR STRING; 103690.gene:10495482; -.
DR MEROPS; C26.A25; -.
DR KEGG; ana:alr3443; -.
DR eggNOG; COG0147; Bacteria.
DR eggNOG; COG0512; Bacteria.
DR Proteomes; UP000002483; Chromosome.
DR GO; GO:0046820; F:4-amino-4-deoxychorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd01743; GATase1_Anthranilate_Synthase; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005802; ADC_synth_comp_1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR006221; TrpG/PapA_dom.
DR NCBIfam; TIGR00553; pabB; 1.
DR NCBIfam; TIGR00566; trpG_papA; 1.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF18; AMINODEOXYCHORISMATE SYNTHASE; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR Pfam; PF00117; GATase; 1.
DR PRINTS; PR00097; ANTSNTHASEII.
DR PRINTS; PR00099; CPSGATASE.
DR PRINTS; PR00096; GATASE.
DR SUPFAM; SSF56322; ADC synthase; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 3: Inferred from homology;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605};
KW Reference proteome {ECO:0000313|Proteomes:UP000002483};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 7..190
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT DOMAIN 244..379
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 428..682
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT ACT_SITE 86
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 174
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 176
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 714 AA; 80400 MW; 64464E5F00ABC8AC CRC64;
MADIKTLIID NYDSYTFNLY QMIAEVNGEL PLVIHNDKLD WYELKQLVFD NIVISPGPGR
PENPKDFGIC QQILQNYLDV PLLGVCLGHQ GIGHYYGGKV IHAPEPKHGR LSHVYHNGGD
LFQEIPTPFQ VVRYHSLLVA EELPSCLEKV AWTEDGLVMG LRHRHLPLWG VQFHPESICS
EYGYKLLENF QAITEGFIRQ NGRHRPKLES KSFSISPNSP IPAPSQEFTV CSQKLDYYLD
TEQTFVHLFG EDPHAFWLDS SLVEPGLSRF SFMGGSGGIN SLLVSYCTQS QELTITQSGK
VTRTQESIFD YLKREINRRR CPSDELPFDF NCGFVGYFGY ELKAKSGSGL EHPSLFPDAI
LILSDRLIAF DHQEQTTYLV YLAPVGETAP AQAWFELTEK RLRTLPPLPP LVPSTTSHPV
TFRLSRSYQT YKDDISRCLK EIREGETYQV CLTNRLCTDT IADPLEFYRR LRQVNPAPYS
AFLRFGEMAI ACSSPERFLQ IDRQGWVETK PIKGTVRRGE TPEEDFLLRE SLRSSEKERS
ENLMIVDLLR NDLGRVCQVG SIHVPKLMDV ESYATVHQLV STIRGLLSPD MDATDCIRLA
FPGGSMTGAP KLRTMEIIDQ LEQEARGVYS GAIGFLGVNG TADLNIVIRT AVLTPNQTSI
GIGGGIVALS DVEMEFQETI LKANALIQAM LLTVHGEYHP SLYRILGMPT EVFC
//
