ID Q8ZJY6_SALTY Unreviewed; 318 AA.
AC Q8ZJY6;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Cobalamin synthesis protein {ECO:0000313|EMBL:AAL23348.1};
GN Name=yjiA {ECO:0000313|EMBL:AAL23348.1};
GN OrderedLocusNames=STM4530 {ECO:0000313|EMBL:AAL23348.1};
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287 {ECO:0000313|EMBL:AAL23348.1, ECO:0000313|Proteomes:UP000001014};
RN [1] {ECO:0000313|EMBL:AAL23348.1, ECO:0000313|Proteomes:UP000001014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720
RC {ECO:0000313|Proteomes:UP000001014};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; AE006468; AAL23348.1; -; Genomic_DNA.
DR RefSeq; NP_463389.1; NC_003197.2.
DR RefSeq; WP_000187839.1; NC_003197.2.
DR AlphaFoldDB; Q8ZJY6; -.
DR SMR; Q8ZJY6; -.
DR STRING; 99287.STM4530; -.
DR PaxDb; 99287-STM4530; -.
DR GeneID; 1256056; -.
DR KEGG; stm:STM4530; -.
DR PATRIC; fig|99287.12.peg.4773; -.
DR HOGENOM; CLU_017452_0_2_6; -.
DR OMA; HSQGFET; -.
DR PhylomeDB; Q8ZJY6; -.
DR BioCyc; SENT99287:STM4530-MONOMER; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001014}.
FT DOMAIN 224..317
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 318 AA; 35609 MW; 6EEDED680DA76A94 CRC64;
MTPIAVTLLT GFLGAGKTTL LRHILNEQHG FKIAVIENEF GEVSVDDQLI GDRATQIKTL
TNGCICCTRS NELEDALLDL LDSRDRGDIA FDRLVIECTG MADPGPIIQT FFSHDVLCER
YLLDGVIALV DAVHANEQMN QFTIAQSQIG YADRILLTKT DVAGDSEKLR ERLARINARA
PVYTVVHGDI DLSQLFNTSG FMLEENVLAS QPRFHFIADK QNDVSSIVVE LDYPVDISEV
SRVMENLLLE SADKLLRYKG MLWIDGEPNR LLFQGVQRLY SADWDRPWGD ETPHSTLVFI
GIQLPEDEIR AAFVGLRK
//
