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Database: UniProt
Entry: Q8ZPM2
LinkDB: Q8ZPM2
Original site: Q8ZPM2 
ID   RSXC_SALTY              Reviewed;         735 AA.
AC   Q8ZPM2;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   10-APR-2019, entry version 117.
DE   RecName: Full=Ion-translocating oxidoreductase complex subunit C {ECO:0000255|HAMAP-Rule:MF_00461};
DE            EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_00461};
DE   AltName: Full=Rsx electron transport complex subunit C {ECO:0000255|HAMAP-Rule:MF_00461};
GN   Name=rsxC {ECO:0000255|HAMAP-Rule:MF_00461};
GN   OrderedLocusNames=STM1457;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA   Waterston R., Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT   LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Part of a membrane-bound complex that couples electron
CC       transfer with translocation of ions across the membrane. Required
CC       to maintain the reduced state of SoxR. {ECO:0000255|HAMAP-
CC       Rule:MF_00461}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00461};
CC       Note=Binds 2 [4Fe-4S] clusters per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_00461};
CC   -!- SUBUNIT: The complex is composed of six subunits: RsxA, RsxB,
CC       RsxC, RsxD, RsxE and RsxG. {ECO:0000255|HAMAP-Rule:MF_00461}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00461}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00461}.
CC   -!- SIMILARITY: Belongs to the 4Fe4S bacterial-type ferredoxin family.
CC       RnfC subfamily. {ECO:0000255|HAMAP-Rule:MF_00461}.
DR   EMBL; AE006468; AAL20379.1; -; Genomic_DNA.
DR   RefSeq; NP_460420.1; NC_003197.2.
DR   RefSeq; WP_000915668.1; NC_003197.2.
DR   ProteinModelPortal; Q8ZPM2; -.
DR   PaxDb; Q8ZPM2; -.
DR   PRIDE; Q8ZPM2; -.
DR   EnsemblBacteria; AAL20379; AAL20379; STM1457.
DR   GeneID; 1252975; -.
DR   KEGG; stm:STM1457; -.
DR   PATRIC; fig|99287.12.peg.1540; -.
DR   eggNOG; ENOG4107QTR; Bacteria.
DR   eggNOG; COG4656; LUCA.
DR   HOGENOM; HOG000279299; -.
DR   KO; K03615; -.
DR   OMA; QQLYWYS; -.
DR   PhylomeDB; Q8ZPM2; -.
DR   BioCyc; SENT99287:STM1457-MONOMER; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; -; 1.
DR   Gene3D; 3.40.50.11540; -; 1.
DR   HAMAP; MF_00461; RsxC_RnfC; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR010208; Ion_transpt_RnfC/RsxC.
DR   InterPro; IPR011538; Nuo51_FMN-bd.
DR   InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR   InterPro; IPR026902; RnfC_N.
DR   InterPro; IPR019554; Soluble_ligand-bd.
DR   PANTHER; PTHR43034; PTHR43034; 2.
DR   Pfam; PF01512; Complex1_51K; 1.
DR   Pfam; PF12838; Fer4_7; 1.
DR   Pfam; PF13375; RnfC_N; 1.
DR   Pfam; PF10531; SLBB; 1.
DR   SUPFAM; SSF142019; SSF142019; 1.
DR   SUPFAM; SSF46548; SSF46548; 1.
DR   TIGRFAMs; TIGR01945; rnfC; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   3: Inferred from homology;
KW   4Fe-4S; Cell inner membrane; Cell membrane; Complete proteome;
KW   Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding;
KW   Reference proteome; Repeat; Translocase; Transport.
FT   CHAIN         1    735       Ion-translocating oxidoreductase complex
FT                                subunit C.
FT                                /FTId=PRO_0000073212.
FT   DOMAIN      368    397       4Fe-4S ferredoxin-type 1.
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   DOMAIN      407    436       4Fe-4S ferredoxin-type 2.
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       377    377       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       380    380       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       383    383       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       387    387       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       416    416       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       419    419       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       422    422       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       426    426       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
SQ   SEQUENCE   735 AA;  78698 MW;  EB54EEDF14039612 CRC64;
     MLKLFSAFRK DKIWDFDGGI HPPEMKTQSN GTPLRQVPLA PRFVIPLKQH IGAEGELCVS
     VGDRVLRGQA LTRGRGRMLP VHAPTSGTVI AIAPHSTAHP SALAELSVII DADGEDRWIE
     REGWSDYRAH SREALIERIH QYGVAGLGGA GFPTGVKLQG GGDKITTLII NAAECEPYIT
     ADDRLMQDCA AQIVEGIRIL AHILQPREVL IGIEDNKPQA ISMLRAVLAD AHDISLRVIP
     TKYPSGGAKQ LTRILTGKQV PHGGRSSDIG VLMQNVGTAY AVKRAVIDGE PITERVVTLT
     GEAVSRPGNV WARLGTPVRH LLNDAGFCPS ADQMVIMGGP LMGFTLPWLD VPVVKITNCL
     LAPSVTEMGA PQEEKSCIRC SACADACPAD LLPQQLYWFS KGQQHDKATA HHIADCIECG
     ACAWVCPSNI PLVQYFRQEK AEINAIRLEE KRAAEAKARF EARQARLERE KAARLARHKS
     AAVQPAAKDQ DAIAAALARV KEKQAQATQP VVIQAGSQPD NSAVIAAREA RKAQARAKQA
     AHPMADSAIP GDDPSKAAVE AAIARAKARK QEQQAGSEPA EPVDPRKAAV EAAIARAKAR
     KQEQQAGSEP VEAVDPRKAA VEAAIARAKA RKQEQQTGSE PAEAVDPRKA AVEAAIARAK
     ARKQEQQTGS EPAEPIDPRK AAVEAAIARA KARKQEQQAG SEPAEPADPR KAAVAAAIAR
     VQAKKAAQQQ VVNED
//
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