ID   Q8ZRS1_SALTY            Unreviewed;       796 AA.
AC   Q8ZRS1;
DT   01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT   01-MAR-2002, sequence version 1.
DT   27-MAR-2024, entry version 118.
DE   SubName: Full=Glucose dehydrogenase {ECO:0000313|EMBL:AAL19133.1};
DE            EC=1.1.5.2 {ECO:0000313|EMBL:AAL19133.1};
GN   Name=gcd {ECO:0000313|EMBL:AAL19133.1};
GN   OrderedLocusNames=STM0169 {ECO:0000313|EMBL:AAL19133.1};
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287 {ECO:0000313|EMBL:AAL19133.1, ECO:0000313|Proteomes:UP000001014};
RN   [1] {ECO:0000313|EMBL:AAL19133.1, ECO:0000313|Proteomes:UP000001014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720
RC   {ECO:0000313|Proteomes:UP000001014};
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- COFACTOR:
CC       Name=pyrroloquinoline quinone; Xref=ChEBI:CHEBI:58442;
CC         Evidence={ECO:0000256|ARBA:ARBA00001931};
CC   -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00008156}.
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DR   EMBL; AE006468; AAL19133.1; -; Genomic_DNA.
DR   RefSeq; NP_459174.1; NC_003197.2.
DR   RefSeq; WP_000829731.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZRS1; -.
DR   STRING; 99287.STM0169; -.
DR   PaxDb; 99287-STM0169; -.
DR   GeneID; 1251687; -.
DR   KEGG; stm:STM0169; -.
DR   PATRIC; fig|99287.12.peg.179; -.
DR   HOGENOM; CLU_018478_1_0_6; -.
DR   PhylomeDB; Q8ZRS1; -.
DR   BioCyc; SENT99287:STM0169-MONOMER; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0008876; F:quinoprotein glucose dehydrogenase activity; IBA:GO_Central.
DR   CDD; cd10280; PQQ_mGDH; 1.
DR   Gene3D; 2.140.10.10; Quinoprotein alcohol dehydrogenase-like superfamily; 1.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR017511; PQQ_mDH.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR001479; Quinoprotein_DH_CS.
DR   NCBIfam; TIGR03074; PQQ_membr_DH; 1.
DR   PANTHER; PTHR32303; QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C); 1.
DR   PANTHER; PTHR32303:SF4; QUINOPROTEIN GLUCOSE DEHYDROGENASE; 1.
DR   Pfam; PF01011; PQQ; 5.
DR   SMART; SM00564; PQQ; 6.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   PROSITE; PS00364; BACTERIAL_PQQ_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:AAL19133.1}; PQQ {ECO:0000256|ARBA:ARBA00022891};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001014};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        41..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   796 AA;  86495 MW;  0E90312EF2251E27 CRC64;
     MAENNARSPR LLVTLTALFA ALCGLYLLIG GVWLVAIGGS WYYPIAGLVM LVVAGLLWRS
     KRAALWLYAA LLLATMIWGV WEVGFDFWAL TPRSDILVFF GIWLILPFVW HRLVVPSSGA
     VAALVVALLI SGGILTWAGF NDPQEINGTL RADATPAATS SSIADEDWPA YGRNQEGQRY
     SPLKQITADN VHQLKEAWVF RTGDLKQPND PGEITNEVTP IKVGDTLYLC TAHQRLFALD
     AASGKEKWHF DPQLKTDSSF QHVTCRGVSY HEAKADTASP EVIADCPRRI ILPVNDGRLF
     AVNAETGKLC ETFANKGVLN LQTNMPDTTP GLYEPTSPPI ITDKTIVIAG SVTDNFSTRE
     TSGVIRGFDV NSGKLMWAFD PGAKDPNAIP ADEHAFTFNS PNSWAPAAYD AKLDLVYLPM
     GVTTPDIWGG NRTPEQERYA SSILALNATT GKLAWSYQTV HHDLWDMDLP AQPTLADITV
     DGTTVPVIYA PAKTGNIFVL DRRNGELVVP APEKPVPQGA AKGDYVAKTQ PFSDLTFRPK
     KDLSGADMWG ATMFDQLVCR VMFHQLRYEG IFTPPSEQGT LVFPGNLGMF EWGGISVDPD
     RQVAIANPMA LPFVSKLIPR GPGNPMEPPK DAKGTGTEAG IQPQYGVPFG VTLNPFLSPF
     GLPCKQPAWG YISALDLKTN EIVWKKRIGT PRDSMPFPMP VPVPFNMGMP MLGGPISTAG
     NVLFIAATAD NYLRAYNMSN GEKLWQGRLP AGGQATPMTY EVNGKQYVVV SAGGHGSFGT
     KMGDYIVAYA LPDDAK
//