ID Q8ZRW4_SALTY Unreviewed; 629 AA.
AC Q8ZRW4;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Sulfatase {ECO:0000313|EMBL:AAL19048.1};
GN OrderedLocusNames=STM0084 {ECO:0000313|EMBL:AAL19048.1};
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287 {ECO:0000313|EMBL:AAL19048.1, ECO:0000313|Proteomes:UP000001014};
RN [1] {ECO:0000313|EMBL:AAL19048.1, ECO:0000313|Proteomes:UP000001014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720
RC {ECO:0000313|Proteomes:UP000001014};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; AE006468; AAL19048.1; -; Genomic_DNA.
DR RefSeq; NP_459089.1; NC_003197.2.
DR RefSeq; WP_000066317.1; NC_003197.2.
DR AlphaFoldDB; Q8ZRW4; -.
DR STRING; 99287.STM0084; -.
DR PaxDb; 99287-STM0084; -.
DR GeneID; 1251602; -.
DR KEGG; stm:STM0084; -.
DR PATRIC; fig|99287.12.peg.87; -.
DR HOGENOM; CLU_006332_8_0_6; -.
DR OMA; INSCVCT; -.
DR PhylomeDB; Q8ZRW4; -.
DR BioCyc; SENT99287:STM0084-MONOMER; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0004065; F:arylsulfatase activity; IBA:GO_Central.
DR GO; GO:0015024; F:glucuronate-2-sulfatase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16035; sulfatase_like; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR46615; ARYLSULFATASE K; 1.
DR PANTHER; PTHR46615:SF1; ARYLSULFATASE K; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001014}.
FT DOMAIN 67..439
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 629 AA; 71747 MW; A2BC0729D9929033 CRC64;
MSNKKNLSAE ETDLTRRKLL TSAGILAAGG MLSGAVKADE KCAVKAKPAW DKPFTGEIPE
KLPEGYNILL VVTDQERFFP TFPFPVPGRE RLMKTGVTFC NHQNTSNVCT PSRSVLYTGL
HMPQTKMFDN LGLPWMPYDL DPALGTTGHM MRELGYYTAY KGKWHLTEKL EKPLPDEKDE
DIDVGDIPEP ELHKIMEKYG FADYHGIGDI IGHSKGGYFY DSTTTAQTIN WLRCKGQPLN
DQHKPWFLAV NLVNPHDVMF IDTDKEGEKV QWRGELDQDD NTLAPTQPPE NELYQASWPN
YPLPANRHQS FNEQGRPPAH LEYQTARAAL EGQFPDEDRR WRKLLDYYFN CIRDCDTHLD
RILNELDALK LTDKTIVVFT ADHGELGGSH QMHGKGASVY KEQIHVPMII SHPAYPGNKK
CQALTCHLDI APTLVGLTGL PEEKQHQALG NRKGVNFSGL LKNPESVAVN AVRNASLYCY
GMILYTDAHY LHRVIALQRD KQKTVAQIKQ EISHLHPDFS HRSGTRMIND GRYKFARYFS
LREHNTPETW EDLIKYNDLE LYDLKNDPDE NHNLAADKQK YQDLILTMNE KLNKIIKDEI
GVDDGSFMPD AAHEPWDLTI EQFNRMAKD
//
