ID Q8ZS83_NOSS1 Unreviewed; 463 AA.
AC Q8ZS83;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 106.
DE SubName: Full=Nickel resistance protein {ECO:0000313|EMBL:BAB77272.1};
GN OrderedLocusNames=all7629 {ECO:0000313|EMBL:BAB77272.1};
OS Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OG Plasmid pCC7120beta {ECO:0000313|EMBL:BAB77272.1,
OG ECO:0000313|Proteomes:UP000002483}.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=103690 {ECO:0000313|EMBL:BAB77272.1, ECO:0000313|Proteomes:UP000002483};
RN [1] {ECO:0000313|EMBL:BAB77272.1, ECO:0000313|Proteomes:UP000002483}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576
RC {ECO:0000313|Proteomes:UP000002483};
RC PLASMID=Plasmid pCC7120beta {ECO:0000313|Proteomes:UP000002483};
RX PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT "Complete genomic sequence of the filamentous nitrogen-fixing
RT cyanobacterium Anabaena sp. strain PCC 7120.";
RL DNA Res. 8:205-213(2001).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AP003602; BAB77272.1; -; Genomic_DNA.
DR PIR; AB2543; AB2543.
DR RefSeq; WP_010993957.1; NZ_RSCN01000012.1.
DR AlphaFoldDB; Q8ZS83; -.
DR KEGG; ana:all7629; -.
DR OrthoDB; 9775268at2; -.
DR Proteomes; UP000002483; Plasmid pCC7120beta.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR004751; Drug_antiport.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR NCBIfam; TIGR00900; 2A0121; 1.
DR PANTHER; PTHR43266:SF2; LYSOPHOSPHOLIPID TRANSPORTER LPLT; 1.
DR PANTHER; PTHR43266; MACROLIDE-EFFLUX PROTEIN; 1.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:BAB77272.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002483};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 26..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..401
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 463 AA; 51060 MW; 1DFD8E3EBD17BBC2 CRC64;
MNTLTFFRSL RNPVFARLYT AQTTSLLGDA LTWVGLALLA FNLAGKNAAV VLSVALTLRV
TAFVLLSPLA GAIADRLDRK KIMVVTHIFR MLIVGMLPFV TQIWQVYVLI FALNVFNAFF
TPTYQATIPL VTSENDYAGA IALSSATYQL LGVLGPGIAG SVAAFIGARQ VFFLDALSFA
IAAVLIFTLP GQLVVAQNQQ PSRTTRRTWG DIKDGTTRLL TDAPIRYALA MQLVASIAGA
QILVNTVGYV QGTLKFGEVQ YGWVMAAFGI GATLCAVIYG TFNRSLPRTT FVFIGATLIT
LALLPANYAN LTVLMVLWLV AGAGQNLVNL PTQTLIADRI PTAIQGRVYG AHFAWSHLWW
AISYPLAGWL GSHFAEREFI YGSLVGLMLL VVVQITLSPH PHEHEHLQYV TVHKHKHIHD
ECHQHDHDEG IVIAEPHNHL HEHTRILYHT HPHTRDIHHR HSH
//
