ID Q8ZTW4_PYRAE Unreviewed; 546 AA.
AC Q8ZTW4;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE RecName: Full=RCK C-terminal domain-containing protein {ECO:0000259|PROSITE:PS51202};
GN OrderedLocusNames=PAE3063 {ECO:0000313|EMBL:AAL64645.1};
OS Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS 104966 / NBRC 100827 / IM2).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=178306 {ECO:0000313|EMBL:AAL64645.1, ECO:0000313|Proteomes:UP000002439};
RN [1] {ECO:0000313|EMBL:AAL64645.1, ECO:0000313|Proteomes:UP000002439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 /
RC IM2 {ECO:0000313|Proteomes:UP000002439};
RX PubMed=11792869; DOI=10.1073/pnas.241636498;
RA Fitz-Gibbon S.T., Ladner H., Kim U.J., Stetter K.O., Simon M.I.,
RA Miller J.H.;
RT "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT aerophilum.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE009441; AAL64645.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8ZTW4; -.
DR STRING; 178306.PAE3063; -.
DR EnsemblBacteria; AAL64645; AAL64645; PAE3063.
DR KEGG; pai:PAE3063; -.
DR PATRIC; fig|178306.9.peg.2302; -.
DR eggNOG; arCOG00237; Archaea.
DR HOGENOM; CLU_509633_0_0_2; -.
DR InParanoid; Q8ZTW4; -.
DR Proteomes; UP000002439; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR43652; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR PANTHER; PTHR43652:SF2; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002439};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 24..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 268..351
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 546 AA; 58975 MW; CDDB0549236C4C1B CRC64;
MDIWFVATVS AVLAAVTLSF KYRADIIAFV SLMALVLVGV YDLREALSYL ISPAVIVLFG
SMVISGVIAD SGLLDRVARY ISVRVRHVAT ASLLLYFVAG VASGFVSDVA IVLAMAVLIG
DVAKRLGASP AAYVIPLAFA AAIGGRLTMV GNAGNVILLD IYQTTTGEKL NILAFTAPAL
LALAISVPLL LLISFYAQRF VPQLSTAVKF LVVTTEVGET LDGKTRQEVE KAYRVKILTK
DRILLKYSTV LVKIAVSDIP SFMTSKDLIL RPLGNNKGEH MEFLIVTQRS RLVGKTLALE
PIHNVFPVSI IGIVPSGPVE SLESYVFRPG DEILVLGDEK VIERIAAYYR LERSKTLVKA
FNPRLAASGI SGLFAAVVLS QFAPASLAFI IGTFIALLGG GKAVERLYQY VSWETLIYVG
SFLAIGTAAA RIDLLKPITP LLNSPEYLFV IGLFLTNTLG LIPSAVLIGP YLTTKEMLMT
YVLATIPILL PPAHPAIYLI YREYGLSIKD FLKISIPATA IAILATGIAV YLYYNLPIQT
PIFQLP
//
