ID Q8ZV49_PYRAE Unreviewed; 421 AA.
AC Q8ZV49;
DT 01-MAR-2002, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2002, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Arsenite transport protein, conjectural {ECO:0000313|EMBL:AAL64207.1};
GN OrderedLocusNames=PAE2457 {ECO:0000313|EMBL:AAL64207.1};
OS Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS 104966 / NBRC 100827 / IM2).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=178306 {ECO:0000313|EMBL:AAL64207.1, ECO:0000313|Proteomes:UP000002439};
RN [1] {ECO:0000313|EMBL:AAL64207.1, ECO:0000313|Proteomes:UP000002439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 /
RC IM2 {ECO:0000313|Proteomes:UP000002439};
RX PubMed=11792869; DOI=10.1073/pnas.241636498;
RA Fitz-Gibbon S.T., Ladner H., Kim U.J., Stetter K.O., Simon M.I.,
RA Miller J.H.;
RT "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT aerophilum.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000256|ARBA:ARBA00009843}.
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DR EMBL; AE009441; AAL64207.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8ZV49; -.
DR STRING; 178306.PAE2457; -.
DR EnsemblBacteria; AAL64207; AAL64207; PAE2457.
DR KEGG; pai:PAE2457; -.
DR PATRIC; fig|178306.9.peg.1831; -.
DR eggNOG; arCOG00238; Archaea.
DR HOGENOM; CLU_011920_3_0_2; -.
DR InParanoid; Q8ZV49; -.
DR Proteomes; UP000002439; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR CDD; cd01117; YbiR_permease; 1.
DR InterPro; IPR000802; Arsenical_pump_ArsB.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR PANTHER; PTHR43302; TRANSPORTER ARSB-RELATED; 1.
DR PANTHER; PTHR43302:SF5; TRANSPORTER ARSB-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR PRINTS; PR00758; ARSENICPUMP.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002439};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..350
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 421 AA; 45024 MW; C3403B5CA5D06594 CRC64;
MTADAAVALL LAALVVGGMV ARPIYPKLPT WSLMSLAAFI AVFLGPLTVD DVPRVINVEV
VLFLVGMFSI VALAELSGLL DAFAYWFVSL FKSRLSVYTA SSLLFGLLSA FAVNDTVALM
GPPVAAAIAR ASGIEYRHMF LLLAFSLTIG SVMTPIGNPQ NMLIAVESGI KAPFITFLSR
LAIPTLINLI ITPVVLFKIL GIKNERVSFV ALPKELIKNG RDAAVAAVVL IGTVAAMAAN
DLAALSGHPH IHNIGFIPFV AASLLYFFAS SPREVLARVE WGTVIFFLAM FITMEAIWRG
GILQPIISAV LPTYTGSAYD ILAITAISLF LSQVLSNVPF VSLFSTYLHS LGVTDPKAWL
TLAMASTIAG NLTLLGAASN IIILEVLETR FHSTITFAQF IKYGSLITAI NTAIYLPFLL
I
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