GenomeNet

Database: UniProt
Entry: Q92HJ3
LinkDB: Q92HJ3
Original site: Q92HJ3 
ID   SODF_RICCN              Reviewed;         209 AA.
AC   Q92HJ3;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   16-JAN-2019, entry version 90.
DE   RecName: Full=Superoxide dismutase [Mn/Fe];
DE            EC=1.15.1.1;
GN   Name=sodB; OrderedLocusNames=RC0778;
OS   Rickettsia conorii (strain ATCC VR-613 / Malish 7).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=272944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-613 / Malish 7;
RX   PubMed=11557893; DOI=10.1126/science.1061471;
RA   Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V.,
RA   Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M.,
RA   Raoult D.;
RT   "Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
RL   Science 293:2093-2098(2001).
CC   -!- FUNCTION: Destroys superoxide anion radicals which are normally
CC       produced within the cells and which are toxic to biological
CC       systems.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000250};
CC       Note=Binds 1 Mn(2+) or Fe(2+) ion per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC       family. {ECO:0000305}.
DR   EMBL; AE006914; AAL03316.1; -; Genomic_DNA.
DR   PIR; B97797; B97797.
DR   RefSeq; WP_010977391.1; NC_003103.1.
DR   ProteinModelPortal; Q92HJ3; -.
DR   SMR; Q92HJ3; -.
DR   EnsemblBacteria; AAL03316; AAL03316; RC0778.
DR   GeneID; 927465; -.
DR   KEGG; rco:RC0778; -.
DR   HOGENOM; HOG000013584; -.
DR   KO; K04564; -.
DR   OMA; KWGSFDK; -.
DR   BioCyc; RCON272944:G1FZG-1281-MONOMER; -.
DR   Proteomes; UP000000816; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 2.40.500.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019833; Mn/Fe_SOD_BS.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
DR   PROSITE; PS00088; SOD_MN; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Iron; Manganese; Metal-binding; Oxidoreductase.
FT   CHAIN         1    209       Superoxide dismutase [Mn/Fe].
FT                                /FTId=PRO_0000159998.
FT   METAL        38     38       Manganese or iron. {ECO:0000250}.
FT   METAL        90     90       Manganese or iron. {ECO:0000250}.
FT   METAL       172    172       Manganese or iron. {ECO:0000250}.
FT   METAL       176    176       Manganese or iron. {ECO:0000250}.
SQ   SEQUENCE   209 AA;  24648 MW;  DC0FF9CDB954D74F CRC64;
     MTYCNKSNQT SYPFILPDLP YEKESFKPHF TLETFDYHHG KHHNTYVQNL NNLLKDKEEL
     QKKDLEEIIE WSSQNSNAAI FNNAAQIWNH TFFWHSIKPQ GGGKPSGKIL EQINKDFGSF
     EEFCEQFKQE AVGQFGSGWA WLIYHDNRLQ IIKTANAGTP IAHGMKPLLA CDVWEHAYYI
     DYRNKRPDYV DIFIKHMINW KFVEDNLIK
//
DBGET integrated database retrieval system