ID Q92NJ1_RHIME Unreviewed; 381 AA.
AC Q92NJ1;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:CAC46790.1};
DE EC=1.1.1.- {ECO:0000313|EMBL:CAC46790.1};
GN ORFNames=SMc01582 {ECO:0000313|EMBL:CAC46790.1};
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834 {ECO:0000313|EMBL:CAC46790.1, ECO:0000313|Proteomes:UP000001976};
RN [1] {ECO:0000313|EMBL:CAC46790.1, ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|EMBL:CAC46790.1,
RC ECO:0000313|Proteomes:UP000001976};
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2] {ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|Proteomes:UP000001976};
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
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DR EMBL; AL591688; CAC46790.1; -; Genomic_DNA.
DR RefSeq; NP_386317.1; NC_003047.1.
DR RefSeq; WP_010969773.1; NC_003047.1.
DR AlphaFoldDB; Q92NJ1; -.
DR EnsemblBacteria; CAC46790; CAC46790; SMc01582.
DR GeneID; 61603675; -.
DR KEGG; sme:SMc01582; -.
DR PATRIC; fig|266834.11.peg.3679; -.
DR eggNOG; COG1454; Bacteria.
DR HOGENOM; CLU_007207_0_0_5; -.
DR OrthoDB; 9815791at2; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd14861; Fe-ADH-like; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
DR PROSITE; PS00060; ADH_IRON_2; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CAC46790.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001976}.
FT DOMAIN 10..371
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 381 AA; 40213 MW; 04748ED4D20705E2 CRC64;
MTITANWSYP TAVKFGAGRI KELADHCKAL GIKKPLLVTD RGLAPMAITQ QALDILEAGG
LGRAIFADVD PNPNDRNLEA GVKAFRDGGH DGVVAFGGGS GLDLGKCVAF MAGQTRPVWD
FEDIGDWWTR ASVEGIAPIV AVPTTAGTGS EVGRASVITN SASHVKKVIF HPKFLPGVTI
CDPELTVGMP KVITAGTGMD AFAHCLEAYS SPFYHPMSAG IALEGMRLVK EYLPRAYKDG
ADLEARANMM SAAAMGAVAF QKGLGAIHSL SHPVGAIYNT HHGMTNAVVM PPVLRFNRSA
IEEKIGRAAA YLGIAGGFDG FYDYVLRLRE ELGVPDKLSA LGVGTDRIDE MAEMAIVDPT
AGGNPVELTL DAAEKLFAEC I
//
