ID Q92NN4_RHIME Unreviewed; 611 AA.
AC Q92NN4;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE SubName: Full=Aminopeptidase P {ECO:0000313|EMBL:CAC46736.1};
GN ORFNames=SMc01885 {ECO:0000313|EMBL:CAC46736.1};
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834 {ECO:0000313|EMBL:CAC46736.1, ECO:0000313|Proteomes:UP000001976};
RN [1] {ECO:0000313|EMBL:CAC46736.1, ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|EMBL:CAC46736.1,
RC ECO:0000313|Proteomes:UP000001976};
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2] {ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|Proteomes:UP000001976};
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; AL591688; CAC46736.1; -; Genomic_DNA.
DR RefSeq; NP_386263.1; NC_003047.1.
DR RefSeq; WP_010969733.1; NC_003047.1.
DR AlphaFoldDB; Q92NN4; -.
DR EnsemblBacteria; CAC46736; CAC46736; SMc01885.
DR GeneID; 61603621; -.
DR KEGG; sme:SMc01885; -.
DR PATRIC; fig|266834.11.peg.3622; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_1_5; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:CAC46736.1};
KW Hydrolase {ECO:0000313|EMBL:CAC46736.1};
KW Protease {ECO:0000313|EMBL:CAC46736.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001976}.
FT DOMAIN 17..138
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 324..538
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 548..609
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 611 AA; 66015 MW; 2F78AA356AEF58C5 CRC64;
MFQSFEVTST PQFGKERTTA LRAALATLGV DGFLVPRADE FQGEYVPRSS ERLSWLTGFT
GSAGVALVTQ REAIVFVDGR YVTQLKEQVD GSVFTGGDLI GEPPHVWLER HGPKGFRLGI
DPWLHTAAEV RRLEKALAAI GGSVVLLDHN PLDRLWTDRP ATPLGPVTIQ PVEHAGQLAK
DKIAEIAAGV AKAKAAAVVL TDPSSVAWTF NIRGSDVPHT PHPLARAIIH ADGSAELFLD
KRKTGIEQEA YLTQLADIMA PASFDDRLAA LASTGAAIMI DPDLAPFAIG ELIRRKEGSV
VEAVDPARLP RACKNAAEIA GSTRAHLQDG AAMVEFLAWL DGREPGSVTE IGATRQLEAT
RAAVGERMQN PLKDVSFDTI AGAGSHAAIM HYRVTNETDR RIEAGTMFLI DSGAQYINGT
TDITRTVAIG AVPEEQKRFF TLVLKGMIAI STARFPKGSR GVDLDPLARI ALWKAGADYA
HGTGHGVGSY LSVHEGPQRI ARLATQELLP GMILSNEPGY YRPGAFGIRI ENLVVVREPE
EIEGGDQPML GFDTLTFCPI DRRLVLPALL TDDELDWLNA YHAETLEKLM PLLSGTETRD
WLASATEAIV R
//
