ID Q92S44_RHIME Unreviewed; 481 AA.
AC Q92S44;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=TolC family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SMc02281 {ECO:0000313|EMBL:CAC45157.1};
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834 {ECO:0000313|EMBL:CAC45157.1, ECO:0000313|Proteomes:UP000001976};
RN [1] {ECO:0000313|EMBL:CAC45157.1, ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|EMBL:CAC45157.1,
RC ECO:0000313|Proteomes:UP000001976};
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2] {ECO:0000313|Proteomes:UP000001976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021 {ECO:0000313|Proteomes:UP000001976};
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
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DR EMBL; AL591688; CAC45157.1; -; Genomic_DNA.
DR RefSeq; NP_384691.1; NC_003047.1.
DR RefSeq; WP_010968680.1; NC_003047.1.
DR AlphaFoldDB; Q92S44; -.
DR EnsemblBacteria; CAC45157; CAC45157; SMc02281.
DR GeneID; 61602057; -.
DR KEGG; sme:SMc02281; -.
DR PATRIC; fig|266834.11.peg.1962; -.
DR eggNOG; COG1538; Bacteria.
DR HOGENOM; CLU_043115_0_0_5; -.
DR OrthoDB; 237412at2; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR003423; OMP_efflux.
DR PANTHER; PTHR30203:SF24; BLR4935 PROTEIN; 1.
DR PANTHER; PTHR30203; OUTER MEMBRANE CATION EFFLUX PROTEIN; 1.
DR Pfam; PF02321; OEP; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001976};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..481
FT /note="TolC family protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004318779"
SQ SEQUENCE 481 AA; 51896 MW; D18A3333B5CB8679 CRC64;
MMKARMKLAA TLALPLVLGG CVTAGEYAVK NAGFSLVAAT TAEAADKQTV WVQNQEQARS
VSERVKTLMA KKAIDVETAV QVALLNNKGL QAAYADLGES AADAWQATML VNPTVGVGLT
GIGTPGLTAF RTVEGAIVSN ILALVTRDRN IALADTEFRK AQLDAASRTL QLASETRRAW
INAVAAWETV GQLNQAQAAA DAASELAEKL GESGAMTKGS QAREHVFYAE LAGEGAKARL
EARLAKEELT RLMGLWGSDV KFQVPNRLAS LPKGLMKRDQ IEAEALRRRV DLQMAKLDLE
ATARSYNLTE ATRYVTDLNL LAGFETERAK EDGDISSETT GRVDLEFAIP IFDSGKARMR
KAELAYMRAA NLLAEKAVNV RSEARSAYQA YRANYDIARH YRNSVVPLRT KIEEQSLLTY
NGMITSTFEL LADSREKVNS ILLAINAKRD FWLAEADLAP AIYGGGASGE TEVAAAAESG
N
//
