ID Q93RX7_STRCO Unreviewed; 662 AA.
AC Q93RX7;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 140.
DE SubName: Full=ABC transporter ATP-binding protein {ECO:0000313|EMBL:CAC37897.1};
GN OrderedLocusNames=SCO6295 {ECO:0000313|EMBL:CAC37897.1};
GN ORFNames=SCBAC8D1.08 {ECO:0000313|EMBL:CAC37897.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAC37897.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAC37897.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AL939127; CAC37897.1; -; Genomic_DNA.
DR RefSeq; NP_630393.1; NC_003888.3.
DR RefSeq; WP_011030802.1; NZ_VNID01000022.1.
DR AlphaFoldDB; Q93RX7; -.
DR STRING; 100226.gene:17763954; -.
DR PaxDb; 100226-SCO6295; -.
DR PATRIC; fig|100226.15.peg.6410; -.
DR eggNOG; COG1132; Bacteria.
DR HOGENOM; CLU_000604_84_5_11; -.
DR InParanoid; Q93RX7; -.
DR OrthoDB; 9806127at2; -.
DR PhylomeDB; Q93RX7; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0034040; F:ATPase-coupled lipid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF658; ABC TRANSPORTER B FAMILY MEMBER 29, CHLOROPLASTIC; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:CAC37897.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..319
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 353..587
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 591..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 71511 MW; 3B3EF12BEF8A26DB CRC64;
MTTDTRGPAP GRSAVVLALR HYGRELLRLR RLALPALLLP AVGNIGIRYI APLLIAKLAG
QAADDGGLTL GRALPYVLGF GLTLLLAEAV WRVGQHCLNR VDALGMEHLY VSGMDELLAK
DAAFFHDNFA GSLTKRVLSF GKRFEDFVDT VTYRIVGSLV PLVFGAVVLW SYEPMLVVGL
FLMIGLTVVA ATPLIRRRQR LVNDREAAIA RVSGHVADSL MNMETVRAFA AERREAAEHR
GRVADSRRLT LRSWDYGNLR VDTLIAPMSV LTNVLGLLVA IAFGGPGQGV EEVVVAFTYY
SNATQIMFEF NQIYRRLESS TTEAAQFTEL LLDPPTVVDA DAPAPLAPRD SGIRFEAVTF
AHAGAKPIFR GLDLDVPAGA RIGLVGRSGG GKTTLTRLLL RMSDIERGRI LIGGQDISLL
RQSDLRSLIA YVPQEPAMLH RSLRDNIAFA RPGATDEEIH AAAAAAHVTE FADQLPDGFG
TLVGERGVKL SGGQRQRVAL ARAILRDAPV LLLDEATSAL DSESELLVQD ALWRLMDGRT
ALVVAHRLST VAGMDRLVVL DRGRVVEQGP HEKLLAADGA YARLWRHQSG GFLGESTGPT
VDGDGRDDGD GRDDGDGRVD GDGRDDGDRR DDGDRRGGGP PHVRPRRESS GPPSEEAARS
AP
//
