ID Q93XB9_TOBAC Unreviewed; 249 AA.
AC Q93XB9;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Bax inhibitor 1 {ECO:0000313|EMBL:AAK73102.1, ECO:0000313|RefSeq:XP_016470953.1};
GN Name=BI-1 {ECO:0000313|EMBL:AAK73102.1};
GN Synonyms=LOC107793180 {ECO:0000313|RefSeq:XP_016470953.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|EMBL:AAK73102.1};
RN [1] {ECO:0000313|EMBL:AAK73102.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:AAK73102.1};
RX PubMed=12520328;
RA Bolduc N., Ouellet M., Pitre F., Brisson L.F.;
RT "Molecular characterization of two plant BI-1 homologues which suppress
RT Bax-induced apoptosis in human 293 cells.";
RL Planta 216:377-386(2003).
RN [2] {ECO:0000313|Proteomes:UP000084051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TN90 {ECO:0000313|Proteomes:UP000084051};
RX PubMed=24807620; DOI=10.1038/ncomms4833;
RA Sierro N., Battey J.N., Ouadi S., Bakaher N., Bovet L., Willig A.,
RA Goepfert S., Peitsch M.C., Ivanov N.V.;
RT "The tobacco genome sequence and its comparison with those of tomato and
RT potato.";
RL Nat. Commun. 5:3833-3833(2014).
RN [3] {ECO:0000313|RefSeq:XP_016470953.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000256|RuleBase:RU004379}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF390556; AAK73102.1; -; mRNA.
DR RefSeq; NP_001312488.1; NM_001325559.1.
DR RefSeq; XP_016470953.1; XM_016615467.1.
DR STRING; 4097.Q93XB9; -.
DR PaxDb; 4097-Q93XB9; -.
DR GeneID; 107793180; -.
DR KEGG; nta:107793180; -.
DR OMA; AQKISNC; -.
DR OrthoDB; 56151at2759; -.
DR Proteomes; UP000084051; Unplaced.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR CDD; cd10430; BI-1; 1.
DR InterPro; IPR006214; Bax_inhibitor_1-related.
DR PANTHER; PTHR23291; BAX INHIBITOR-RELATED; 1.
DR PANTHER; PTHR23291:SF129; GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN-RELATED; 1.
DR Pfam; PF01027; Bax1-I; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004379};
KW Reference proteome {ECO:0000313|Proteomes:UP000084051};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU004379};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU004379}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 67..86
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 92..113
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 120..141
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 147..164
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 176..195
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
FT TRANSMEM 215..237
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU004379"
SQ SEQUENCE 249 AA; 27605 MW; 776ECC35BEBFB9F8 CRC64;
MESCTSFFNS QSASSRNRWS YDSLKNFRQI SPFVQTHLKK VYLSLCCALV ASAAGAYLHI
LWNIGGLLTT LGCVGSIVWL MATPLYEEQK RIALLMAAAL FKGASIGPLI ELAIDFDPSI
VIGAFVGCAV AFGCFSAAAM VARRREYLYL GGLLSSGLSI LFWLHFASSI FGGSMALFKF
EVYFGLLVFV GYIIFDTQDI IEKAHLGDLD YVKHALTLFT DFVAVFVRIL IIMLKNASDK
EEKKKKRRN
//
