ID Q93YW4_ARATH Unreviewed; 532 AA.
AC Q93YW4;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 141.
DE SubName: Full=Proline-rich spliceosome-associated (PSP) family protein / zinc knuckle (CCHC-type) family protein {ECO:0000313|EMBL:AED94340.1};
GN Name=MBB18.15 {ECO:0000313|EMBL:AED94340.1};
GN Synonyms=MBB18_15 {ECO:0000313|EMBL:AED94340.1};
GN OrderedLocusNames=At5g38600 {ECO:0000313|Araport:AT5G38600,
GN ECO:0000313|EMBL:AED94340.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAL24150.1};
RN [1] {ECO:0000313|EMBL:AED94340.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130714; DOI=10.1038/35048507;
RG Kazusa DNA Research Institute;
RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium;
RG European Union Arabidopsis Genome Sequencing Consortium;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., See L.H., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Dusterhoft A., Stiekema W., Pohl T., Entian K.D.,
RA Terryn N., Hartley N., Bent E., Johnson S., Langham S.A., McCullagh B.,
RA Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H.,
RA Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Lankhorst R.K., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S.,
RA Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J.,
RA Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.W., Bevan M., Fransz P.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2] {ECO:0000313|EMBL:AAL24150.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Liu S.X., Sakano H., Pham P.K., Banh J., Chung M.K.,
RA Goldsmith A.D., Lee J.M., Quach H.L., Toriumi M., Yu G., Bowser L.,
RA Carninci P., Chen H., Cheuk R., Hayashizaki Y., Ishida J., Jones T.,
RA Kamiya A., Karlin-Neumann G., Kawai J., Kim C., Lam B., Lin J., Miranda M.,
RA Narusaka M., Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P.,
RA Southwick A., Shinozaki K., Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Full Length cDNA Clones.";
RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAM20101.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Banh J., Chan M.M., Chang C.H., Chang E., Dale J.M., Deng J.M.,
RA Goldsmith A.D., Lee J.M., Onodera C.S., Quach H.L., Tang C., Toriumi M.,
RA Wu H.C., Yamamura Y., Yu G., Bowser L., Carninci P., Chen H., Cheuk R.,
RA Hayashizaki Y., Ishida J., Jones T., Kamiya A., Karlin-Neumann G.,
RA Kawai J., Kim C., Lam B., Lin J., Meyers M.C., Miranda M., Narusaka M.,
RA Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P.,
RA Southwick A., Shinozaki K., Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Open Reading Frame (ORF) Clones.";
RL Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0007829|PubMed:19245862}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [5] {ECO:0000313|EMBL:AED94340.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:AED94340.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
CC -!- SIMILARITY: Belongs to the ZCCHC8 family.
CC {ECO:0000256|ARBA:ARBA00007497}.
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DR EMBL; AY059738; AAL24150.1; -; mRNA.
DR EMBL; AY096461; AAM20101.1; -; mRNA.
DR EMBL; CP002688; AED94340.1; -; Genomic_DNA.
DR RefSeq; NP_568558.1; NM_123221.4.
DR AlphaFoldDB; Q93YW4; -.
DR IntAct; Q93YW4; 3.
DR STRING; 3702.Q93YW4; -.
DR PaxDb; 3702-AT5G38600-1; -.
DR ProteomicsDB; 191897; -.
DR EnsemblPlants; AT5G38600.1; AT5G38600.1; AT5G38600.
DR GeneID; 833850; -.
DR Gramene; AT5G38600.1; AT5G38600.1; AT5G38600.
DR Araport; AT5G38600; -.
DR TAIR; AT5G38600; -.
DR eggNOG; KOG2673; Eukaryota.
DR HOGENOM; CLU_029670_2_0_1; -.
DR OrthoDB; 1275937at2759; -.
DR PRO; PR:Q93YW4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q93YW4; baseline and differential.
DR GO; GO:0062141; C:nuclear exosome targeting complex; ISS:TAIR.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR006568; PSP_pro-rich.
DR InterPro; IPR001878; Znf_CCHC.
DR PANTHER; PTHR13316:SF10; PROLINE-RICH SPLICEOSOME-ASSOCIATED (PSP) FAMILY PROTEIN _ ZINC KNUCKLE (CCHC-TYPE) FAMILY PROTEIN; 1.
DR PANTHER; PTHR13316; ZINC FINGER, CCHC DOMAIN CONTAINING 8; 1.
DR Pfam; PF04046; PSP; 1.
DR SMART; SM00581; PSP; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q93YW4,
KW ECO:0007829|ProteomicsDB:Q93YW4};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 242..258
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 264..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 362..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..532
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 532 AA; 60550 MW; B8BF45F18D8BD8F2 CRC64;
METEDVLDIP ASSNFGSEVK KNSLESGNGS PEANSLVGND ENVKGNLDLD LTEENLRIVG
GQESGEILTE QVSDVFNASV ESVAVDEKLG IQKETLVHST TLDVSSKAGV KRPRTSYDEQ
QPTVHVTYKH LTRASKQKLE SLLQKWSEWE AENTSLAQDQ EQLFESGEET CFPAIRVGLQ
KTSSVSFWID NQTGHKPLED FVLVESSTTP LYDRKFAIGL NSADGSRNVE GGLEIIDDDP
PRCFNCGGYS HSLRECPRPF DRSAVNSARK LQKSKRNQNS SGPRLPSRYY QKTQTGKYDG
LKPGTLDAET RQLLNLGELD PPPWLNRMRE IGYPPGYLAP EDDHLSGITI FGEEVETREE
IESEDGEILE KANHPPEPQM KKTVEFPGIN APFPENADEW LWEAAPSHRN SSRSGRWQQQ
KTSRGHDYRD DGPLGVEPSS YPPRYGSRYD YGYGSNEYGS RSRSPGIDRS LSERSKRDYS
SYDADFRERD RDRDRNRDRD RDRDWDRDRD RDCDRDRDRD DRDWSYRLSS RR
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