ID Q94K56_ARATH Unreviewed; 324 AA.
AC Q94K56;
DT 01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 162.
DE RecName: Full=GrpE protein homolog {ECO:0000256|RuleBase:RU000640};
GN Name=EMB1241 {ECO:0000313|EMBL:AED92458.1,
GN ECO:0000313|TAIR:AT5G17710};
GN Synonyms=embryo defective 1241 {ECO:0000313|EMBL:AED92458.1}, MVA3.60
GN {ECO:0000313|EMBL:AED92458.1}, MVA3_60 {ECO:0000313|EMBL:AED92458.1};
GN OrderedLocusNames=At5g17710 {ECO:0000313|Araport:AT5G17710,
GN ECO:0000313|EMBL:AED92458.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAK44101.1};
RN [1] {ECO:0000313|EMBL:AED92458.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130714; DOI=10.1038/35048507;
RG Kazusa DNA Research Institute;
RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium;
RG European Union Arabidopsis Genome Sequencing Consortium;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., See L.H., Vil D., Baker J.,
RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Dusterhoft A., Stiekema W., Pohl T., Entian K.D.,
RA Terryn N., Hartley N., Bent E., Johnson S., Langham S.A., McCullagh B.,
RA Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H.,
RA Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Lankhorst R.K., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S.,
RA Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J.,
RA Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K., Rudd S., Schoof H.,
RA Schueller C., Zaccaria P., Mewes H.W., Bevan M., Fransz P.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2] {ECO:0000313|EMBL:AAK44101.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Liu S.X., Sakano H., Pham P.K., Banh J., Chung M.K.,
RA Goldsmith A.D., Lee J.M., Quach H.L., Toriumi M., Yu G., Bowser L.,
RA Carninci P., Chen H., Cheuk R., Hayashizaki Y., Ishida J., Jones T.,
RA Kamiya A., Karlin-Neumann G., Kawai J., Kim C., Lam B., Lin J., Miranda M.,
RA Narusaka M., Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P.,
RA Southwick A., Shinozaki K., Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Full Length cDNA Clones.";
RL Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAL34228.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Liu S.X., Sakano H., Pham P.K., Banh J., Etgu P., Lee J.M.,
RA Toriumi M., Yu G., Brooks S., Chao Q., Chen H., Karlin-Neumann G., Kim C.,
RA Lam B., Miranda M., Nguyen M., Palm C.J., Shinn P., Southwick A.,
RA Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Open Reading Frame (ORF) Clones.";
RL Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AED92458.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AED92458.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Essential component of the PAM complex, a complex required
CC for the translocation of transit peptide-containing proteins from the
CC inner membrane into the mitochondrial matrix in an ATP-dependent
CC manner. {ECO:0000256|RuleBase:RU000640}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|RuleBase:RU000640}.
CC -!- SIMILARITY: Belongs to the GrpE family. {ECO:0000256|ARBA:ARBA00009054,
CC ECO:0000256|RuleBase:RU004478}.
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DR EMBL; AF370286; AAK44101.1; -; mRNA.
DR EMBL; AY063054; AAL34228.1; -; mRNA.
DR EMBL; CP002688; AED92458.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM70271.1; -; Genomic_DNA.
DR RefSeq; NP_001318588.1; NM_001343522.1.
DR RefSeq; NP_568356.1; NM_121777.3.
DR AlphaFoldDB; Q94K56; -.
DR SMR; Q94K56; -.
DR EnsemblPlants; AT5G17710.1; AT5G17710.1; AT5G17710.
DR EnsemblPlants; AT5G17710.3; AT5G17710.3; AT5G17710.
DR GeneID; 831638; -.
DR Gramene; AT5G17710.1; AT5G17710.1; AT5G17710.
DR Gramene; AT5G17710.3; AT5G17710.3; AT5G17710.
DR KEGG; ath:AT5G17710; -.
DR Araport; AT5G17710; -.
DR TAIR; AT5G17710; EMB1241.
DR HOGENOM; CLU_057217_5_1_1; -.
DR OMA; REDSNEY; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q94K56; baseline and differential.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0051087; F:protein-folding chaperone binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR CDD; cd00446; GrpE; 1.
DR Gene3D; 3.90.20.20; -; 1.
DR Gene3D; 2.30.22.10; Head domain of nucleotide exchange factor GrpE; 1.
DR HAMAP; MF_01151; GrpE; 1.
DR InterPro; IPR000740; GrpE.
DR InterPro; IPR013805; GrpE_coiled_coil.
DR InterPro; IPR009012; GrpE_head.
DR PANTHER; PTHR21237; GRPE PROTEIN; 1.
DR PANTHER; PTHR21237:SF27; GRPE PROTEIN HOMOLOG; 1.
DR Pfam; PF01025; GrpE; 1.
DR PRINTS; PR00773; GRPEPROTEIN.
DR SUPFAM; SSF58014; Coiled-coil domain of nucleotide exchange factor GrpE; 1.
DR SUPFAM; SSF51064; Head domain of nucleotide exchange factor GrpE; 1.
DR PROSITE; PS01071; GRPE; 1.
PE 1: Evidence at protein level;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU000640};
KW Mitochondrion {ECO:0000256|RuleBase:RU000640};
KW Proteomics identification {ECO:0007829|PeptideAtlas:Q94K56,
KW ECO:0007829|ProteomicsDB:Q94K56};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548}.
FT REGION 68..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..103
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 324 AA; 35494 MW; 78D74F0A423995E1 CRC64;
MAGLLKTPSL HLTPTLLHAP SVPFKPFCVS FAGGRNVSVS LSRRASLRSV SSGYPLRLLN
LVPFASGEAE TTETEVESNE PEETDGAVDV ENENASAEEG EAEEEEAAVI TALLKSYKEA
LADNNEGKIA EIEASLKSIE DEKFLLADKV ASLSNELSVE RDRLIRISAD FDNFRKRTER
ERLNLVSNAQ GEVVENLLAV LDNFERAKSQ IKVETEGEEK VTNSYQSIYK QFVEILGSLG
VIHVETVGKQ FDPMLHEAIM REDSAEYEEG IVLEEYRKGF LLGERLLRPS MVKVSAGPGP
EKPLEAEGEE ATAQGSAEEE SSSS
//
