ID AIPL1_SAIBB Reviewed; 372 AA.
AC Q95MN7;
DT 10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 22-FEB-2023, entry version 73.
DE RecName: Full=Aryl-hydrocarbon-interacting protein-like 1;
GN Name=AIPL1;
OS Saimiri boliviensis boliviensis (Bolivian squirrel monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Saimiriinae; Saimiri.
OX NCBI_TaxID=39432;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11420621; DOI=10.1007/s003350020024;
RA Sohocki M.M., Sullivan L.S., Tirpak D.L., Daiger S.P.;
RT "Comparative analysis of aryl-hydrocarbon receptor interacting protein-like
RT 1 (Aipl1), a gene associated with inherited retinal disease in humans.";
RL Mamm. Genome 12:566-568(2001).
CC -!- FUNCTION: May be important in protein trafficking and/or protein
CC folding and stabilization. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with NUB1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF296415; AAK77959.1; -; mRNA.
DR RefSeq; NP_001266889.1; NM_001279960.1.
DR AlphaFoldDB; Q95MN7; -.
DR SMR; Q95MN7; -.
DR STRING; 39432.ENSSBOP00000013223; -.
DR GeneID; 101051406; -.
DR CTD; 23746; -.
DR OrthoDB; 11153at2759; -.
DR Proteomes; UP000233220; Whole Genome Shotgun Assembly.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.
DR Gene3D; 3.10.50.40; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR039663; AIP/AIPL1/TTC9.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR11242; ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED; 1.
DR PANTHER; PTHR11242:SF2; ARYL-HYDROCARBON-INTERACTING PROTEIN-LIKE 1; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..372
FT /note="Aryl-hydrocarbon-interacting protein-like 1"
FT /id="PRO_0000075348"
FT DOMAIN 53..145
FT /note="PPIase FKBP-type"
FT REPEAT 178..211
FT /note="TPR 1"
FT REPEAT 230..263
FT /note="TPR 2"
FT REPEAT 264..297
FT /note="TPR 3"
FT REGION 325..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..362
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 42961 MW; 1EFC2FA9C49A35C4 CRC64;
MDAALLLNVE GVKKTILHGG TGELPNFITG SRVIFHFRTM KCDEERTVID DSREVGQPMH
IIIGNMFKLE VWEILLTSMR VREVAEFWCD TIHTGVYPIL SRSLRQMAQG KDPTEWHVHT
CGLANMFAYH TLGYEDLDEL QKEPQPLIFV IELLQVDAPS DYQRETWNLS NHEKMKVVPV
LHGEGNRLFK LGRYEEASSK YQEAIICLRN LQTKEKPWEV QWLKLEKMIN TLILNYCQCL
LKKEEYYEVL EHTSDILRHH PGIVKAYYVR ARAHAEVWNE AEAKADLQKV LELEPSMQKA
VRRELRLLEN RMAEKQEEER LRCRNMLSQG ATWSPAEPPA EPPAESSTEP PAEPPAEPPA
ELTLTPGHPL QH
//
