ID AIPL1_PAPCY Reviewed; 372 AA.
AC Q95MN8;
DT 10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 24-JAN-2024, entry version 72.
DE RecName: Full=Aryl-hydrocarbon-interacting protein-like 1;
GN Name=AIPL1;
OS Papio cynocephalus (Yellow baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9556;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11420621; DOI=10.1007/s003350020024;
RA Sohocki M.M., Sullivan L.S., Tirpak D.L., Daiger S.P.;
RT "Comparative analysis of aryl-hydrocarbon receptor interacting protein-like
RT 1 (Aipl1), a gene associated with inherited retinal disease in humans.";
RL Mamm. Genome 12:566-568(2001).
CC -!- FUNCTION: May be important in protein trafficking and/or protein
CC folding and stabilization. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with NUB1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
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DR EMBL; AF296414; AAK77958.1; -; mRNA.
DR AlphaFoldDB; Q95MN8; -.
DR SMR; Q95MN8; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.
DR Gene3D; 3.10.50.40; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR039663; AIP/AIPL1/TTC9.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR11242; ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED; 1.
DR PANTHER; PTHR11242:SF2; ARYL-HYDROCARBON-INTERACTING PROTEIN-LIKE 1; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Repeat; TPR repeat.
FT CHAIN 1..372
FT /note="Aryl-hydrocarbon-interacting protein-like 1"
FT /id="PRO_0000075346"
FT DOMAIN 53..145
FT /note="PPIase FKBP-type"
FT REPEAT 178..211
FT /note="TPR 1"
FT REPEAT 230..263
FT /note="TPR 2"
FT REPEAT 264..297
FT /note="TPR 3"
FT REGION 315..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..362
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 372 AA; 42907 MW; FB4512AAFAA9E307 CRC64;
MDAALLLNVE GVKKTILHGG TGELPNFITG SRVIFHFRTM KCDEERTVID DSRQVDQPMH
IIIGNMFKLE VWEILLTSMR VHEVAEFWCD TIHTGVYPIL SRSLRQMAQG KDPTEWHVHT
CGLANMFAYH TLGYEDLDEL QKEPQPLIFV IELLQVDAPS DYQRETWNLS NHEKMKVVPV
LHGEGNRLFK LGRYEEASSK YQEAIICLRN LQTKEKPWEV QWLKLEKMIN TLTLNYCQCL
LKKEEYYEVL EHTSDILRHH PGIVKAYYVR ARAHAEVWNE AEAKADLQKV LELEPSMQKA
VRRELRLLEN RMAEKQEEER LRCRNMLSQG ATQPPTEPPA EPHTAPPAEL STGPPAEPPA
ELPLSPGHSL QH
//
