ID Q97H10_CLOAB Unreviewed; 638 AA.
AC Q97H10;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:AAK80162.1};
GN OrderedLocusNames=CA_C2205 {ECO:0000313|EMBL:AAK80162.1};
OS Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS / VKM B-1787).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK80162.1, ECO:0000313|Proteomes:UP000000814};
RN [1] {ECO:0000313|EMBL:AAK80162.1, ECO:0000313|Proteomes:UP000000814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC {ECO:0000313|Proteomes:UP000000814};
RX PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE001437; AAK80162.1; -; Genomic_DNA.
DR PIR; G97171; G97171.
DR RefSeq; NP_348822.1; NC_003030.1.
DR RefSeq; WP_010965503.1; NC_003030.1.
DR AlphaFoldDB; Q97H10; -.
DR STRING; 272562.CA_C2205; -.
DR GeneID; 44998684; -.
DR KEGG; cac:CA_C2205; -.
DR PATRIC; fig|272562.8.peg.2406; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_0_1_9; -.
DR OrthoDB; 9776025at2; -.
DR Proteomes; UP000000814; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:AAK80162.1};
KW Cilium {ECO:0000313|EMBL:AAK80162.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:AAK80162.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 24..135
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 320..625
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 638 AA; 68556 MW; 69529F6CF252693C CRC64;
MSSTSGTGST SAYNSPMRMT GLASGLDVDS IVSKLMQPYE MKRDTMKQDE TYLEWKRDAY
RAVTTSSATL SSTYFDQLNQ DNYMLTPNAY ADYTGISDDN TNTTSDASKD TGVIAKGHEG
TAEGNYSVTV NRVGTTARNA NTLTGQTVTD AGGKTYTLSD SGSAVAANGG NDTLTVVFNG
KTQDFKLGNM SVDDTLKSVA SYFNLTVTSS TLDGQYHISA NSSIGGNIFQ SGTTGKVTSG
ATVDSSAPAD TVVGVGGISG GKGALGAVDY NASGNNFFKN IFGLSGTNTS TAASVTAIDG
NSKTKTLSNV TGINMIDGVN ANVTITEPNG SKGTVESMNN DFSVDGVEYD ISKINLAESG
SVYTPHKANI QMTLNVDKIY NKITGFIDKY NAYVQQINDK INETKTYSYK PLTDAQKKAM
TDDEVTKWET QAKQGILAND SYLQSMVTEF RKAFYTGVDG AGFTLTDLGI SSYSGVGDAV
NKAGQMKYDP ATLKTAIKKY GSSIYNIFAK QSKDESLYIK NNDINQSSAD IAKTMARRQT
RYSQEGIFQR INDIMQDYTR VNTFPPGTLV QLAGSSTSTD TTSTLTKQIK DKLQAINDYD
STLSDKQEQF YLQYSKLESY LAQAQSQQQS LQSQLSKL
//
