ID Q97ME8_CLOAB Unreviewed; 688 AA.
AC Q97ME8;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:AAK78231.1};
GN OrderedLocusNames=CA_C0250 {ECO:0000313|EMBL:AAK78231.1};
OS Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS / VKM B-1787).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=272562 {ECO:0000313|EMBL:AAK78231.1, ECO:0000313|Proteomes:UP000000814};
RN [1] {ECO:0000313|EMBL:AAK78231.1, ECO:0000313|Proteomes:UP000000814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
RC {ECO:0000313|Proteomes:UP000000814};
RX PubMed=11466286; DOI=10.1128/JB.183.16.4823-4838.2001;
RA Nolling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA Doucette-Stamm L., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; AE001437; AAK78231.1; -; Genomic_DNA.
DR PIR; D96930; D96930.
DR RefSeq; NP_346891.1; NC_003030.1.
DR RefSeq; WP_010963573.1; NC_003030.1.
DR AlphaFoldDB; Q97ME8; -.
DR STRING; 272562.CA_C0250; -.
DR GeneID; 44996746; -.
DR KEGG; cac:CA_C0250; -.
DR PATRIC; fig|272562.8.peg.435; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_19_9; -.
DR OrthoDB; 9814363at2; -.
DR Proteomes; UP000000814; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000814};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 325..383
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 402..659
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT COILED 438..465
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 688 AA; 75469 MW; E7626A5596F86D4E CRC64;
MNKRVIGIKG KVLISSMLVL LLTLVSISGI VIYQVNSKAY NDYMDNSNQQ LKTVSQAINI
FYDQLDKNIN MLATNPVIMK ADSSIETYKN TTQDTQMDAS AKGGIEKEIY EVFEQYGKSH
EGTSYVYMGM PNGEYVQWPK ESAPAGYDPS KRPWFIAAMN KKGSVIRTAP YIYKSSMLTS
NASSFNDQNG KVVGAIGIDV QQSDISNMLN KAKIGKTGYS IIVHNKGFIM ADGKNPKNNF
KEIKDVGITG LDQLLAKDLK SFNVTIDGEK YVVNPYKVEG TDWILASFIT QKELMSGATK
IINIVIISAI TILLLTSILF NFVSGSITKP ILAVTKKVED FANLDFSIDE NSEESKYYNK
KDETGNMVRA FRVMRDNVAE FINKTTDATE RVAASAEELT ATSNETATAS EEVAKTIDEI
ARGASEQAKD TQIATNNVED LGNLLEQDLN NIEELNIAAV KIEKQKEEGF LILRDLIDKT
QKNNDAANNI YNIIMSNNES AEKIEIASTM IESIADQTNL LALNAAIEAA RAGEAGKGFA
VVADEIRKLA EQSNSFTNDI KTIINELKTK SESAVNLMEE TKQIVKEQAS SVEATEGKFS
GIAEEIDSIK TIINKFNQSG KLMGDNKNKI IELMQNLSAI SEENAAGTEE TAASIEEQVA
TIQEIAKSGE SLASIAEELS VVISKFKI
//
