ID Q97WV4_SACS2 Unreviewed; 644 AA.
AC Q97WV4;
DT 01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2001, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=N-methyl hydantoinase A (HuyA-2) {ECO:0000313|EMBL:AAK42196.1};
DE EC=3.5.2.14 {ECO:0000313|EMBL:AAK42196.1};
GN Name=huyA-2 {ECO:0000313|EMBL:AAK42196.1};
GN OrderedLocusNames=SSO2008 {ECO:0000313|EMBL:AAK42196.1};
OS Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS (Sulfolobus solfataricus).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Saccharolobus.
OX NCBI_TaxID=273057 {ECO:0000313|EMBL:AAK42196.1, ECO:0000313|Proteomes:UP000001974};
RN [1] {ECO:0000313|Proteomes:UP000001974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2
RC {ECO:0000313|Proteomes:UP000001974};
RX PubMed=11427726; DOI=10.1073/pnas.141222098;
RA She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
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DR EMBL; AE006641; AAK42196.1; -; Genomic_DNA.
DR PIR; E90367; E90367.
DR RefSeq; WP_010923719.1; NC_002754.1.
DR AlphaFoldDB; Q97WV4; -.
DR STRING; 273057.SSO2008; -.
DR PaxDb; 273057-SSO2008; -.
DR EnsemblBacteria; AAK42196; AAK42196; SSO2008.
DR GeneID; 27428332; -.
DR KEGG; sso:SSO2008; -.
DR PATRIC; fig|273057.12.peg.2083; -.
DR eggNOG; arCOG01511; Archaea.
DR HOGENOM; CLU_002157_1_2_2; -.
DR InParanoid; Q97WV4; -.
DR PhylomeDB; Q97WV4; -.
DR Proteomes; UP000001974; Chromosome.
DR GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IBA:GO_Central.
DR GO; GO:0047423; F:N-methylhydantoinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AAK42196.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001974}.
FT DOMAIN 4..174
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 193..478
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 484..640
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
SQ SEQUENCE 644 AA; 71776 MW; BE33904EDCCD7436 CRC64;
MKCKVAIDIG GTFTDFIILS EVGEVSTIKF LTNPRNPGEV IQNVIKGLNC EVEEVVHATT
LATNALLGQE NLNIPRTALL TTKGFRDVIE IGRQNRPRLY DLYFEKPKQI VPRELRIEVD
ERVNADGEIL KEVDEIEVEE KVSKIKAEAV AVSYLHSYIN PHNELKTKEV LKKYFKYISI
SSEVAPEPRE YERTSTTVIN AALMPIVSSY LENIQSSLPT DNFYIMSSSG GLVDINEALN
KSVQLIESGP AAGVIASASF LPEENLISFD MGGTTAKAGV VINGKFEITS EYEVGGEVHH
GRVVKGSGYP IRFPFVDLAE VSAGGGTIIW RDEANALRVG PISAGADPGP ICYNKGGNKP
TITDANLVLG RLGEELLGGN MKLYKEKALE GLSRLGDPYE VSKVALDLVN LEMARAIRLV
TVERGLDPSN FSLIAFGGAG PQHALYLADE IGIKRVIIPP YPGLFSALGL LLADWRFEAR
KSYPKDLERD FKELENKLIE RLKKVDYFIR YADVRYKGQG WELTIQVPEN VNEIRKVFED
KHLATYGFVM SDREIEIVTI RVFAIRRRVT PKISPTFGNE NKPKEIRKVL IEDDWVNTEV
YVREKLPKGF EIRGPAIIEE YSSTIVVKPG WKALVDDSII MVRE
//
