ID Q99YB8_STRP1 Unreviewed; 184 AA.
AC Q99YB8; Q48WZ6;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 117.
DE SubName: Full=Pyrazinamidase/nicotinamidase {ECO:0000313|EMBL:AAK34512.1};
GN OrderedLocusNames=SPy_1776 {ECO:0000313|EMBL:AAK34512.1};
OS Streptococcus pyogenes serotype M1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=301447 {ECO:0000313|EMBL:AAK34512.1, ECO:0000313|Proteomes:UP000000750};
RN [1] {ECO:0000313|EMBL:AAK34512.1, ECO:0000313|Proteomes:UP000000750}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700294 / SF370 / Serotype M1
RC {ECO:0000313|Proteomes:UP000000750};
RX PubMed=11296296; DOI=10.1073/pnas.071559398;
RA Ferretti J.J., McShan W.M., Adjic D., Savic D., Savic G., Lyon K.,
RA Primeaux C., Sezate S.S., Surorov A.N., Kenton S., Lai H., Lin S., Qian Y.,
RA Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA Clifton S.W., Roe B.A., McLaughlin R.E.;
RT "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; AE004092; AAK34512.1; -; Genomic_DNA.
DR RefSeq; NP_269791.1; NC_002737.2.
DR AlphaFoldDB; Q99YB8; -.
DR SMR; Q99YB8; -.
DR PaxDb; 1314-HKU360_01563; -.
DR KEGG; spy:SPy_1776; -.
DR PATRIC; fig|160490.10.peg.1545; -.
DR HOGENOM; CLU_068979_12_1_9; -.
DR OMA; HYYDEFD; -.
DR Proteomes; UP000000750; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00431; cysteine_hydrolases; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR43540:SF10; ISOCHORISMATASE; 1.
DR PANTHER; PTHR43540; PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000000750}.
FT DOMAIN 3..176
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 184 AA; 20743 MW; 8B306FEF5BFF19A1 CRC64;
MRALISIDYT NDFVADDGKL SAGKSAQAIA TKIAEVTKTA FDQGDYIFFA IDCHDQNDSW
HPESKLFAAH NIKGTTGRHL YGPLAEVYSY MKQHPRVFWI DKRYYSAFSG TDLDIRLRER
GITQLVLTGV LSDICVLHTA IDAYHLGYQL EIVKSAVASL TKESYEWSLA HFEQVLGAKL
INDY
//
