ID Y285_STRP1 Reviewed; 256 AA.
AC Q9A1G5; Q490V7;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 24-JAN-2024, entry version 148.
DE RecName: Full=Probable ABC transporter ATP-binding protein SPy_0285/M5005_Spy0242;
GN OrderedLocusNames=SPy_0285, M5005_Spy0242;
OS Streptococcus pyogenes serotype M1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=301447;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX PubMed=11296296; DOI=10.1073/pnas.071559398;
RA Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA Clifton S.W., Roe B.A., McLaughlin R.E.;
RT "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX PubMed=16088826; DOI=10.1086/432514;
RA Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA Musser J.M.;
RT "Evolutionary origin and emergence of a highly successful clone of serotype
RT M1 group A Streptococcus involved multiple horizontal gene transfer
RT events.";
RL J. Infect. Dis. 192:771-782(2005).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Ycf16 family.
CC {ECO:0000305}.
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DR EMBL; AE004092; AAK33355.1; -; Genomic_DNA.
DR EMBL; CP000017; AAZ50861.1; -; Genomic_DNA.
DR RefSeq; NP_268634.1; NC_002737.2.
DR AlphaFoldDB; Q9A1G5; -.
DR SMR; Q9A1G5; -.
DR PaxDb; 1314-HKU360_00281; -.
DR KEGG; spy:SPy_0285; -.
DR KEGG; spz:M5005_Spy0242; -.
DR PATRIC; fig|160490.10.peg.250; -.
DR HOGENOM; CLU_000604_48_1_9; -.
DR OMA; MAMLEPK; -.
DR Proteomes; UP000000750; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR CDD; cd03217; ABC_FeS_Assembly; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR010230; FeS-cluster_ATPase_SufC.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01978; sufC; 1.
DR PANTHER; PTHR43204; ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43204:SF1; ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW Reference proteome; Transport.
FT CHAIN 1..256
FT /note="Probable ABC transporter ATP-binding protein
FT SPy_0285/M5005_Spy0242"
FT /id="PRO_0000093212"
FT DOMAIN 4..246
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 36..43
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 256 AA; 28110 MW; 0BE63689F9B4962B CRC64;
MSILEINNLH VSIEGKEILK GVNLTLKTGE VAAIMGPNGT GKSTLSAAIM GNPNYEVTQG
QILLDGVNIL DLEVDERARL GLFLAMQYPS EIPGITNAEF MRAAMNAGKA DEDKISVRDF
ITKLDEKMAL LGMKEEMAER YLNEGFSGGE KKRNEILQLL MLEPKFALLD EIDSGLDIDA
LKVVSKGVNE MRGKDFGAMI ITHYQRLLNY ITPDLVHVMM DGRIVLSGDA ALATRLEKEG
YAGIAQDLGI EYKEES
//
