ID Q9A7V0_CAUVC Unreviewed; 425 AA.
AC Q9A7V0;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Sun family protein {ECO:0000313|EMBL:AAK23598.1};
GN OrderedLocusNames=CC_1619 {ECO:0000313|EMBL:AAK23598.1};
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650 {ECO:0000313|EMBL:AAK23598.1, ECO:0000313|Proteomes:UP000001816};
RN [1] {ECO:0000313|EMBL:AAK23598.1, ECO:0000313|Proteomes:UP000001816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15 {ECO:0000313|Proteomes:UP000001816};
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R., Ohta N., Maddock J.R., Potocka I.,
RA Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T.,
RA Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J.,
RA Craven M.B., Khouri H., Shetty J., Berry K., Utterback T., Tran K.,
RA Wolf A., Vamathevan J., Ermolaeva M., White O., Salzberg S.L., Venter J.C.,
RA Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
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DR EMBL; AE005673; AAK23598.1; -; Genomic_DNA.
DR PIR; B87450; B87450.
DR RefSeq; NP_420430.1; NC_002696.2.
DR RefSeq; WP_010919493.1; NC_002696.2.
DR AlphaFoldDB; Q9A7V0; -.
DR SMR; Q9A7V0; -.
DR STRING; 190650.CC_1619; -.
DR EnsemblBacteria; AAK23598; AAK23598; CC_1619.
DR KEGG; ccr:CC_1619; -.
DR PATRIC; fig|190650.5.peg.1646; -.
DR eggNOG; COG0144; Bacteria.
DR HOGENOM; CLU_005316_0_2_5; -.
DR BioCyc; CAULO:CC1619-MONOMER; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22807:SF77; SUN PROTEIN; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000001816};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 145..421
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT ACT_SITE 361
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 263
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 308
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 425 AA; 45710 MW; 66E595DC91D0B0A0 CRC64;
MRDGGRVSAA IEVLTEIEAR HFPVKMALKR WGETARYAGS KDRAFVSGLV LDGLRRKRSL
GWMMADSTAR GVMLGVLAFV WKWPLERIAE AAAEEHGFGA LTDVERERLA APVPIEGAPA
PVAGDYPDWL EPHLARALGA DQAAEMRALS ERAPVDLRVN TLKTDVERCA KALALIDAAP
AGVLATAFRI PAPAAADRTP SVEAVPAFSK GWFEVQDLGS QIAAAVAGDV KGKQVLDFCA
GGGGKTLALA AAMGNSGQIF AHDSDARRLA DTIRRGQRAG VRNLQIRSPI EATPLKGLEG
KIDVVFVDAP CTGAGTWRRH PDAKWRLSPD QLAKRQIEQD SVLEDAAAFV KAGGRMIYVT
CSLLTEENED RVAAFLERHP EFTVKPIALD GVTHVTPEGY LRLTPHRAGT DGFFAAVLQR
ASYTP
//
