ID Q9AC41_CAUVC Unreviewed; 550 AA.
AC Q9AC41;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 126.
DE SubName: Full=Major facilitator family transporter {ECO:0000313|EMBL:AAK22013.1};
GN OrderedLocusNames=CC_0025 {ECO:0000313|EMBL:AAK22013.1};
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650 {ECO:0000313|EMBL:AAK22013.1, ECO:0000313|Proteomes:UP000001816};
RN [1] {ECO:0000313|EMBL:AAK22013.1, ECO:0000313|Proteomes:UP000001816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15 {ECO:0000313|Proteomes:UP000001816};
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R., Ohta N., Maddock J.R., Potocka I.,
RA Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B., DeBoy R.T.,
RA Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Smit J.,
RA Craven M.B., Khouri H., Shetty J., Berry K., Utterback T., Tran K.,
RA Wolf A., Vamathevan J., Ermolaeva M., White O., Salzberg S.L., Venter J.C.,
RA Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE005673; AAK22013.1; -; Genomic_DNA.
DR PIR; A87252; A87252.
DR RefSeq; NP_418845.1; NC_002696.2.
DR RefSeq; WP_010917915.1; NC_002696.2.
DR AlphaFoldDB; Q9AC41; -.
DR SMR; Q9AC41; -.
DR STRING; 190650.CC_0025; -.
DR EnsemblBacteria; AAK22013; AAK22013; CC_0025.
DR KEGG; ccr:CC_0025; -.
DR PATRIC; fig|190650.5.peg.26; -.
DR eggNOG; COG0477; Bacteria.
DR HOGENOM; CLU_001265_39_2_5; -.
DR BioCyc; CAULO:CC0025-MONOMER; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17369; MFS_ShiA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 3.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR43045; SHIKIMATE TRANSPORTER; 1.
DR PANTHER; PTHR43045:SF1; SHIKIMATE TRANSPORTER; 1.
DR Pfam; PF00083; Sugar_tr; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 2.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001816};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 51..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..545
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 550 AA; 58746 MW; 9BBD49025259FE83 CRC64;
MAEEGQKRAS MRTVVSASSA GTAFEWYDFF IFGSLTQVIS KTFFAGLNET AGYIAALALF
GVGFAFRPLG ALVFGKIGDQ DGRKGAFLAT VLLMGGATFA IAFLPTYEQA GIIAPILLII
LRCLQGFALG GEYGGAAIYV AEHSPANKRG WATSWVQTSA AFGLFGALLV ILATRWVLGK
YVGPDAFDEW GWRIPFAVSL GLLGISVWMR LKLTESPTFE AMKAEGQASK APYAEAFGQW
SNLKLVILAF VSMMCAQGAV WYTSFFYVQT FMEKFLKVDP VTINELMMIA TAVSAIFYVV
FGWLSDKVGR KPVMLGGMTL ALLFYFPGFH LLEKAANPAL AEASAKAPVV VFADPKDCSL
QFDPVGKTAF VTSCDIVKST LANAGVSYAN EAAPAGAVAV MRIGGAEVLS KSAAGLGKDE
VKATKAEVEG RIKAALAGAG YPTKADPARM NMPMILGVLF VFVIAATALF GPLAACLVEL
FPTRVRYTAL SLPYHIGTGW VGGFVPFFAF AIVAAVGNIY AGLWYPFAFT LLSVLTTLFL
LPETKERPLN
//
