ID Q9B6E5_YARLI Unreviewed; 663 AA.
AC Q9B6E5;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 24-JAN-2024, entry version 105.
DE SubName: Full=COX1-i7 protein, alternatively spliced {ECO:0000313|EMBL:CAC28094.2};
GN Name=cox1 {ECO:0000313|EMBL:CAC28094.2};
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OG Mitochondrion {ECO:0000313|EMBL:CAC28094.2}.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591 {ECO:0000313|EMBL:CAC28094.2, ECO:0000313|Proteomes:UP000001300};
RN [1] {ECO:0000313|EMBL:CAC28094.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=W29 {ECO:0000313|EMBL:CAC28094.2};
RX PubMed=18628906; DOI=10.1002/cfg.72;
RA Kerscher S., Durstewitz G., Casaregola S., Gaillardin C., Brandt U.;
RT "The complete mitochondrial genome of Yarrowia lipolytica.";
RL Comp. Funct. Genomics 2:80-90(2001).
RN [2] {ECO:0000313|EMBL:CAC28094.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=W29 {ECO:0000313|EMBL:CAC28094.2};
RA Kerscher S.J.;
RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the LAGLIDADG
CC endonuclease family. {ECO:0000256|ARBA:ARBA00009332}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the heme-copper
CC respiratory oxidase family. {ECO:0000256|ARBA:ARBA00010468}.
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DR EMBL; AJ307410; CAC28094.2; -; Genomic_DNA.
DR RefSeq; NP_075426.2; NC_002659.1.
DR AlphaFoldDB; Q9B6E5; -.
DR STRING; 284591.Q9B6E5; -.
DR GeneID; 802606; -.
DR KEGG; yli:YalifMp05; -.
DR InParanoid; Q9B6E5; -.
DR OrthoDB; 5387269at2759; -.
DR Proteomes; UP000001300; Mitochondrion.
DR GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IBA:GO_Central.
DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IBA:GO_Central.
DR GO; GO:0006314; P:intron homing; IEA:UniProtKB-KW.
DR GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IBA:GO_Central.
DR Gene3D; 1.20.210.10; Cytochrome c oxidase-like, subunit I domain; 1.
DR Gene3D; 3.10.28.10; Homing endonucleases; 2.
DR InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
DR InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
DR InterPro; IPR000883; Cyt_C_Oxase_1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR004860; LAGLIDADG_2.
DR PANTHER; PTHR10422; CYTOCHROME C OXIDASE SUBUNIT 1; 1.
DR PANTHER; PTHR10422:SF18; CYTOCHROME C OXIDASE SUBUNIT 1; 1.
DR Pfam; PF00115; COX1; 1.
DR Pfam; PF00961; LAGLIDADG_1; 2.
DR PRINTS; PR01165; CYCOXIDASEI.
DR SUPFAM; SSF81442; Cytochrome c oxidase subunit I-like; 1.
DR SUPFAM; SSF55608; Homing endonucleases; 2.
DR PROSITE; PS50855; COX1; 1.
PE 3: Inferred from homology;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Intron homing {ECO:0000256|ARBA:ARBA00022886};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000313|EMBL:CAC28094.2};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000001300};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..374
FT /note="Cytochrome oxidase subunit I profile"
FT /evidence="ECO:0000259|PROSITE:PS50855"
SQ SEQUENCE 663 AA; 74982 MW; 1318001570D61AAA CRC64;
MSLKLNIQRW LFSTNAKDIA VLYFIFALFS AMIGTGLSAI IRLELANTGS PFLHGNTQAF
NVVITAHAIL MIFFFVMPAL VGGFGNYLMP LMLGASDMAF ARLNNISFWL LVPSLILILT
SALVEAGAGT GWTVYFPLAG IQSHSGPAVD LAIFSLHLSG FSSLLGAINF ITTFINMRTI
GMKYENVPLF AWAVLFTAIL LLLSLPVLAA GLTMGIFDRN FNTSFFEYAG GGDAVLYQHL
FYWWNHPEVY ILIIPGFGII SHAVSAIASK PVFGVQGMIY AMWSIGLLGF CVWSHHMFAV
GLDSDTRAYF TSATMVIAVP TSIKIFSWLA TLYGGTIRLN VTALFALGFI FLFTIGGLTG
VVLANSALDI PFHDRKLNKR FSSQKTPLKD PSLLNIKNDL ERGANNILPF FVGLFDGDGN
IQVNHWRKKN LQFRLVIELL NNIGNVRMLN LITKELGGKI IFSGIKVKWT MNDAQEIIKL
CNIFKEYPLL TKKKRYQLAF LQTFYSIYKN IDKELAMKLY FELRNNKYDS NTYKYLNNKT
GCNNNYIPIN YNKIDQVYFC NWFAGFIESE GSFSLRVSNN HSFSFSQKDY ELMLYCKTFF
NIPNKIRDIG NNSYLLECYK KELLDKFTIF FNKYPLYGNK LDQFIEFKNA RDKTNFCPPS
EDK
//
