GenomeNet

Database: UniProt
Entry: Q9BI71_CAEEL
LinkDB: Q9BI71_CAEEL
Original site: Q9BI71_CAEEL 
ID   Q9BI71_CAEEL            Unreviewed;       469 AA.
AC   Q9BI71;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   31-JUL-2019, entry version 130.
DE   SubName: Full=EPsiN (Endocytic protein) homolog {ECO:0000313|EMBL:CAC35825.1};
GN   Name=epn-1 {ECO:0000313|EMBL:CAC35825.1,
GN   ECO:0000313|WormBase:T04C10.2b};
GN   ORFNames=CELE_T04C10.2 {ECO:0000313|EMBL:CAC35825.1}, T04C10.2
GN   {ECO:0000313|WormBase:T04C10.2b};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239 {ECO:0000313|EMBL:CAC35825.1, ECO:0000313|Proteomes:UP000001940};
RN   [1] {ECO:0000313|EMBL:CAC35825.1, ECO:0000313|Proteomes:UP000001940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2 {ECO:0000313|EMBL:CAC35825.1,
RC   ECO:0000313|Proteomes:UP000001940};
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RA   Sulson J.E., Waterston R.;
RT   "Genome sequence of the nematode C. elegans: a platform for
RT   investigating biology.";
RL   Science 282:2012-2018(1998).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; BX284606; CAC35825.1; -; Genomic_DNA.
DR   RefSeq; NP_510458.1; NM_078057.4.
DR   SMR; Q9BI71; -.
DR   IntAct; Q9BI71; 4.
DR   STRING; 6239.T04C10.2b; -.
DR   EPD; Q9BI71; -.
DR   PaxDb; Q9BI71; -.
DR   PeptideAtlas; Q9BI71; -.
DR   EnsemblMetazoa; T04C10.2b; T04C10.2b; WBGene00001329.
DR   GeneID; 181577; -.
DR   UCSC; T04C10.2b; c. elegans.
DR   CTD; 181577; -.
DR   WormBase; T04C10.2b; CE26821; WBGene00001329; epn-1.
DR   eggNOG; KOG2056; Eukaryota.
DR   eggNOG; ENOG410XSM0; LUCA.
DR   GeneTree; ENSGT00940000173221; -.
DR   HOGENOM; HOG000008298; -.
DR   InParanoid; Q9BI71; -.
DR   OMA; EQEYGKS; -.
DR   OrthoDB; 1263849at2759; -.
DR   PhylomeDB; Q9BI71; -.
DR   Reactome; R-CEL-182971; EGFR downregulation.
DR   Reactome; R-CEL-8856825; Cargo recognition for clathrin-mediated endocytosis.
DR   Reactome; R-CEL-8856828; Clathrin-mediated endocytosis.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00001329; Expressed in 5 organ(s), highest expression level in pharyngeal muscle cell (C elegans).
DR   ExpressionAtlas; Q9BI71; baseline and differential.
DR   GO; GO:0030128; C:clathrin coat of endocytic vesicle; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IDA:WormBase.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IDA:WormBase.
DR   GO; GO:0032009; C:early phagosome; IDA:WormBase.
DR   GO; GO:0001891; C:phagocytic cup; IDA:WormBase.
DR   GO; GO:0005886; C:plasma membrane; IDA:WormBase.
DR   GO; GO:0031143; C:pseudopodium; IDA:WormBase.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR027319; Epsin-2_metazoa.
DR   InterPro; IPR003903; UIM_dom.
DR   PANTHER; PTHR12276:SF50; PTHR12276:SF50; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00726; UIM; 2.
DR   SUPFAM; SSF48464; SSF48464; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50330; UIM; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001940};
KW   Proteomics identification {ECO:0000213|EPD:Q9BI71,
KW   ECO:0000213|PeptideAtlas:Q9BI71};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT   DOMAIN       12    143       ENTH. {ECO:0000259|PROSITE:PS50942}.
FT   REGION      152    192       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      267    294       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      324    352       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      428    469       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    165    190       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   469 AA;  51018 MW;  28A57E2C65DD9931 CRC64;
     MSISTIRRQV KNVAYNFSDA QVKVREATSN DPWGPSTALM SEIADLTHNP MAFTEIMSIV
     WKRLNDSGKN WRHVYKSLVL LDFLIKCGHE KVAQQCRENV FTIETLKDFQ HVEDNRDQGL
     NIREKAKQIT SLLSDDERLK NERTRFILTR NKFKQNNPGP VGAESRRSNR HHVTDASLDP
     EYEDARPSTA TEEEMQLQIA LALSREECEK ADEMRKSDDA RLQMALEESQ KLQDADRLAT
     TKQGTVSSGQ LTQSALDDLL SLGVGELVSG NNDQPSSSSA WGMNDPWGAP QASASLNTND
     QMFANSMSNN DPWATSTVAQ PVAATAPNSD PFASWDAPAP AATTPSTMPT SSSFDLLGGD
     LLSPTNSLSA NINTNNSTNG TRKTPENFLG ENSNLVNLDN LLGSGTPSTT GGNPFLTGAA
     PANANPFAAQ QRKSPTLNEM RAAQGQAPPI PSMAPRGTLP QANPFANPF
//
DBGET integrated database retrieval system