ID Q9C893_ARATH Unreviewed; 300 AA.
AC Q9C893;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 127.
DE SubName: Full=Proteinase inhibitor I4, serpin (DUF716) {ECO:0000313|EMBL:AEE33208.1};
GN OrderedLocusNames=At1g55230 {ECO:0000313|EMBL:AAT67566.1};
GN ORFNames=F7A10.19 {ECO:0000313|EMBL:AAG51578.1}, F7A10_19
GN {ECO:0000313|EMBL:AEE33208.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAG51578.1};
RN [1] {ECO:0000313|EMBL:AEE33208.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2] {ECO:0000313|EMBL:AAG51578.1}
RP NUCLEOTIDE SEQUENCE.
RA Lin X., Kaul S., Town C.D., Benito M., Creasy T.H., Haas B.J., Wu D.,
RA Maiti R., Ronning C.M., Koo H., Fujii C.Y., Utterback T.R., Barnstead M.E.,
RA Bowman C.L., White O., Nierman W.C., Fraser C.M.;
RT "Arabidopsis thaliana chromosome 1 BAC F7A10 genomic sequence.";
RL Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAG51578.1}
RP NUCLEOTIDE SEQUENCE.
RA Town C.D., Kaul S.;
RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AAT67566.1}
RP NUCLEOTIDE SEQUENCE.
RA Xiao Y., Underwood B., Moskal W., Torian U., Redman J., Wu H.C.,
RA Utterback T., Town C.D.;
RT "Reconstruction of cDNA sequences for hypothetical genes in Arabidopsis
RT thaliana from 5' and 3' RACE products.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AAX23787.1}
RP NUCLEOTIDE SEQUENCE.
RA Underwood B.A., Xiao Y., Moskal W., Monaghan E., Wang W., Redman J.,
RA Wu H.C., Utterback T., Town C.D.;
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:AEE33208.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:AEE33208.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM45 family.
CC {ECO:0000256|ARBA:ARBA00006948}.
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DR EMBL; AC027034; AAG51578.1; -; Genomic_DNA.
DR EMBL; AY630767; AAT67566.1; -; mRNA.
DR EMBL; AY924712; AAX23787.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33208.1; -; Genomic_DNA.
DR PIR; B96594; B96594.
DR RefSeq; NP_175919.1; NM_104396.3.
DR AlphaFoldDB; Q9C893; -.
DR SMR; Q9C893; -.
DR IntAct; Q9C893; 24.
DR PaxDb; 3702-AT1G55230-1; -.
DR EnsemblPlants; AT1G55230.1; AT1G55230.1; AT1G55230.
DR GeneID; 841966; -.
DR Gramene; AT1G55230.1; AT1G55230.1; AT1G55230.
DR KEGG; ath:AT1G55230; -.
DR TAIR; AT1G55230; -.
DR eggNOG; ENOG502QW4Y; Eukaryota.
DR HOGENOM; CLU_063151_1_0_1; -.
DR OMA; YHLHGRT; -.
DR OrthoDB; 1275684at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C893; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR006904; DUF716.
DR PANTHER; PTHR46285:SF3; PROTEINASE INHIBITOR I4, SERPIN (DUF716); 1.
DR PANTHER; PTHR46285; PROTEINASE INHIBITOR I4, SERPIN (DUF716)-RELATED; 1.
DR Pfam; PF04819; DUF716; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 278..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..293
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 300 AA; 33764 MW; 24FF2E7EF0984573 CRC64;
MGTLVGHVAP GFAFFALGLW HLFNNIKLFC LNPNTFTSSP WFPTSKLRHL ELYIIMVCSS
ISIASELFIG PKKHQPFDSD GTIPSNHLHN FEHSSISMSF LVYAIFAVVL DQERRRSNIS
HGLTMLVASS AFAQQLFLFH LHSADHMGIE GQYHKLLQLI IFVSFLTTLI GITLPKSFLV
SFVRSSSITF QGVWFVVMGY MLWTPSLIPK GCFLHEEEGH QVIKCSSDKA IHRAKSLVNI
EFSWFFVGIT IFVMSLFLIL SGLYGENAEY SILVTKDKGE ESGEEKQDIE SLKKSKPSFG
//
