ID Q9CH78_LACLA Unreviewed; 555 AA.
AC Q9CH78;
DT 01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2001, sequence version 1.
DT 27-MAR-2024, entry version 113.
DE RecName: Full=DNA repair protein RecN {ECO:0000256|ARBA:ARBA00021315, ECO:0000256|PIRNR:PIRNR003128};
DE AltName: Full=Recombination protein N {ECO:0000256|ARBA:ARBA00033408, ECO:0000256|PIRNR:PIRNR003128};
GN Name=recN {ECO:0000313|EMBL:AAK04958.1};
GN ORFNames=L0264 {ECO:0000313|EMBL:AAK04958.1};
OS Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=272623 {ECO:0000313|EMBL:AAK04958.1, ECO:0000313|Proteomes:UP000002196};
RN [1] {ECO:0000313|EMBL:AAK04958.1, ECO:0000313|Proteomes:UP000002196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL1403 {ECO:0000313|EMBL:AAK04958.1,
RC ECO:0000313|Proteomes:UP000002196};
RX PubMed=11337471; DOI=10.1101/gr.GR-1697R;
RA Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA Ehrlich S.D., Sorokin A.;
RT "The complete genome sequence of the lactic acid bacterium Lactococcus
RT lactis ssp. lactis IL1403.";
RL Genome Res. 11:731-753(2001).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000256|PIRNR:PIRNR003128}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000256|ARBA:ARBA00009441,
CC ECO:0000256|PIRNR:PIRNR003128}.
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DR EMBL; AE005176; AAK04958.1; -; Genomic_DNA.
DR PIR; D86732; D86732.
DR RefSeq; NP_267016.1; NC_002662.1.
DR RefSeq; WP_003131352.1; NC_002662.1.
DR AlphaFoldDB; Q9CH78; -.
DR PaxDb; 272623-L0264; -.
DR EnsemblBacteria; AAK04958; AAK04958; L0264.
DR KEGG; lla:L0264; -.
DR PATRIC; fig|272623.7.peg.921; -.
DR eggNOG; COG0497; Bacteria.
DR HOGENOM; CLU_018297_3_1_9; -.
DR OrthoDB; 9806954at2; -.
DR Proteomes; UP000002196; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR CDD; cd03241; ABC_RecN; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR NCBIfam; TIGR00634; recN; 1.
DR PANTHER; PTHR11059; DNA REPAIR PROTEIN RECN; 1.
DR PANTHER; PTHR11059:SF0; DNA REPAIR PROTEIN RECN; 1.
DR Pfam; PF13476; AAA_23; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|PIRNR:PIRNR003128};
KW DNA repair {ECO:0000256|PIRNR:PIRNR003128};
KW Reference proteome {ECO:0000313|Proteomes:UP000002196}.
FT DOMAIN 4..225
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT COILED 159..220
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 347..381
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 555 AA; 62796 MW; B3A5E5A831145C70 CRC64;
MLQEISIKNF AIIEEIHLSF ESGMTILTGE TGAGKSIIID AMSLLLGGRA SSDFVRHGAN
KAEIEGLFFF DKTPELKAVL LELGFEEVDS EIILRREIFA NGRSVCRING QMVNLATLRQ
VGELLVDIHG QHDSQELMNP KSHLRLLDEF GDEAFDQIKN NYKLKFENFK NLRQQLNLRQ
KNEQEFAQRI EILQFQAEEI EAAEINLEED EQLVNRREKL NNIKNIADSL SSAYLALDDE
DNDYSSLNNI RTTMTELDKI SNFDNDYQEL ADKTAESYYV LEEVANQIQR IMSDLEFNPA
ELLQIEDRIM TLTTLKKKYG PELSDVMNYL EKVQLELSEL TGSENDSENL ENSVKVAQVQ
LIEASKKLNE ARHKIAKEVE KDIKHELSEL YMEKADFKVS FEGAKFSANG NEHVEFFIQT
NPGEGFKPLA KTASGGELSR LMLAIKSSFS RRENKTAIVF DEVDTGVSGR VAQAIANKIY
KIARHGQVLA ISHLPQVVAI ADRQFYIEKA STDDITTSTV RKLNAEERVN EIAKMLAGED
LTKEALAQAK RLLSK
//
