ID   Q9CNU8_PASMU            Unreviewed;       680 AA.
AC   Q9CNU8;
DT   01-JUN-2001, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2001, sequence version 1.
DT   27-MAR-2024, entry version 103.
DE   RecName: Full=Lytic murein transglycosylase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=PM0326 {ECO:0000313|EMBL:AAK02410.1};
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843 {ECO:0000313|EMBL:AAK02410.1, ECO:0000313|Proteomes:UP000000809};
RN   [1] {ECO:0000313|EMBL:AAK02410.1, ECO:0000313|Proteomes:UP000000809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70 {ECO:0000313|EMBL:AAK02410.1,
RC   ECO:0000313|Proteomes:UP000000809};
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC   -!- SIMILARITY: Belongs to the transglycosylase Slt family.
CC       {ECO:0000256|ARBA:ARBA00007734}.
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DR   EMBL; AE004439; AAK02410.1; -; Genomic_DNA.
DR   RefSeq; WP_010906589.1; NC_002663.1.
DR   AlphaFoldDB; Q9CNU8; -.
DR   STRING; 272843.PM0326; -.
DR   CAZy; GH23; Glycoside Hydrolase Family 23.
DR   EnsemblBacteria; AAK02410; AAK02410; PM0326.
DR   KEGG; pmu:PM0326; -.
DR   PATRIC; fig|272843.6.peg.339; -.
DR   HOGENOM; CLU_019016_1_0_6; -.
DR   OrthoDB; 92254at2; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0008933; F:lytic transglycosylase activity; IEA:InterPro.
DR   GO; GO:0000270; P:peptidoglycan metabolic process; IEA:InterPro.
DR   CDD; cd13401; Slt70-like; 1.
DR   Gene3D; 1.10.530.10; -; 1.
DR   Gene3D; 1.25.20.10; Bacterial muramidases; 1.
DR   Gene3D; 1.10.1240.20; Lytic transglycosylase, superhelical linker domain; 1.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR037061; Lytic_TGlycoase_superhlx_L_sf.
DR   InterPro; IPR012289; Lytic_TGlycosylase_superhlx_L.
DR   InterPro; IPR008939; Lytic_TGlycosylase_superhlx_U.
DR   InterPro; IPR000189; Transglyc_AS.
DR   InterPro; IPR008258; Transglycosylase_SLT_dom_1.
DR   PANTHER; PTHR37423:SF2; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE; 1.
DR   PANTHER; PTHR37423; SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED; 1.
DR   Pfam; PF00760; Cucumo_coat; 1.
DR   Pfam; PF01464; SLT; 1.
DR   Pfam; PF14718; SLT_L; 1.
DR   SUPFAM; SSF48435; Bacterial muramidases; 1.
DR   SUPFAM; SSF53955; Lysozyme-like; 1.
DR   PROSITE; PS00922; TRANSGLYCOSYLASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000809};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..680
FT                   /note="Lytic murein transglycosylase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004324482"
FT   DOMAIN          443..508
FT                   /note="Lytic transglycosylase superhelical linker"
FT                   /evidence="ECO:0000259|Pfam:PF14718"
FT   DOMAIN          525..631
FT                   /note="Transglycosylase SLT"
FT                   /evidence="ECO:0000259|Pfam:PF01464"
SQ   SEQUENCE   680 AA;  78917 MW;  1B1732929E5C4A8C CRC64;
     MKLTKIALTY LLTLMSMSLA AVSVSVPEDK TQPTEASLTT TNLVQARQIY QKIHQLLQRS
     QSENTQRIVQ ALLAKIEDYP LYPYAQYAYL KALKDQLSLA QIEAFQTDFP SFPLTTELQK
     QWLQQAQDKA EWQAIIHSPF RPKDMASRCI QLQAEYETQP NSPAFSLKQW QQQVAQIWRN
     GASLPKACDT LFARWKEKGY PEETELKERA VLAFEQGNQA LLASLSQQAD QADTKRWLNE
     LHQLSKNPLR LQHPQSAFFI DTLSADDPFA QRILLSHFST LIKRLKETDI KNQHDPFEPY
     AQWANKLRLS EAQQRQWKKH LISHLFDSEN LNLQKWRDAQ LFELKEDTLT ERRLRTALRE
     KTELTPWLDL LSNSAKQKEE WRFWQAKVFA QNKKTTEQAQ QIFQQLAKQR GFYPLLASAE
     LNIDYAPAMD VFSSTSATDI HEKFSVELSR IAELREHNAT QYMNLEWKAL LEKANFEQKL
     ALSQFATEQA WFDLGVEATI QAKAWGYLAL RLPNAYLDWF DLHLNNKNVS RTFAMAIARQ
     ESAWKPYVSS HANAQGLMQL LPSTAKQTAQ EAGLPYTHQK QLFDPFDNIM LGTAHLQQLY
     DKYGNNRILI AAAYNAGASR VDRWLAKADG KLSMAEFIAS IPFYETRGYV QNVLTYDVYY
     QWLQQQPQQK FSQDEYNRLY
//