ID Q9GMZ5_TURTR Unreviewed; 339 AA.
AC Q9GMZ5;
DT 01-MAR-2001, integrated into UniProtKB/TrEMBL.
DT 01-MAR-2001, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Neutrophil cytosol factor 4 {ECO:0000313|RefSeq:NP_001267574.1};
DE SubName: Full=p40-phox {ECO:0000313|EMBL:BAB11805.1};
GN Name=NCF4 {ECO:0000313|RefSeq:NP_001267574.1};
GN Synonyms=p40-phox {ECO:0000313|RefSeq:NP_001267574.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|EMBL:BAB11805.1};
RN [1] {ECO:0000313|EMBL:BAB11805.1, ECO:0000313|RefSeq:NP_001267574.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=11182145; DOI=10.1016/S0165-2427(00)00254-3;
RA Inoue Y., Itou T., Jimbo T., Sakai T., Ueda K., Imajoh-Ohmi S.;
RT "Molecular cloning and identification of bottle-nosed dolphin p40(phox),
RT p47(phox) and p67(phox).";
RL Vet. Immunol. Immunopathol. 78:21-33(2001).
RN [2] {ECO:0000313|RefSeq:NP_001267574.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AB038267; BAB11805.1; -; mRNA.
DR RefSeq; NP_001267574.1; NM_001280645.1.
DR STRING; 9739.ENSTTRP00000008053; -.
DR GeneID; 101340051; -.
DR CTD; 4689; -.
DR OrthoDB; 2997622at2759; -.
DR Proteomes; UP000245320; Chromosome 11.
DR GO; GO:0043020; C:NADPH oxidase complex; IEA:InterPro.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IEA:InterPro.
DR GO; GO:0006909; P:phagocytosis; IEA:InterPro.
DR GO; GO:0045730; P:respiratory burst; IEA:InterPro.
DR CDD; cd06399; PB1_P40; 1.
DR CDD; cd06882; PX_p40phox; 1.
DR CDD; cd11869; SH3_p40phox; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR000919; p40phox.
DR InterPro; IPR035541; p40phox_SH3.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR034853; PB1_P40.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR034912; PX_p40phox.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15706:SF20; NEUTROPHIL CYTOSOL FACTOR 4; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00497; P40PHOX.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 19..140
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 170..229
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 237..329
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
SQ SEQUENCE 339 AA; 39363 MW; B6306ADD3D44E686 CRC64;
MATAQQLRAE SDFNQLPDDI ATSANIADIE EKKGFTSHFV FVIEVKTKGG SKYLIYRRYR
QFYALQSKLE ERFGPENKAS PYICILPTLP AKVYVGVKQE IAEMRIPALN AYMKHLLSLP
IWVLMDEDVR IFFYQSSYDA EQVPQALRRL RPRTRKVKST SPQGAGFDRM AAPRAEALFD
FTGNSKLELN FKVGDVIFLL SRINKDWLEG TVRGTTGIFP VSFVKILKDF PEEEDPTNWL
RCYYYEDTIS TIKDIAVEED LKSTPLFKDL LELMRREFQR EDIALNYQDA EGDLVRLLSD
EDVRLMVKWT QGLPSQKHLF PWKLHITQED NYKVYNTVP
//
